Vomifoliol | CAS:23526-45-6 | Manufacturer ChemFaces

Vomifoliol

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Description:

Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major metabolise, and a cell-free extract exhibits vomifoliol dehydrogenase activity. Vomifoliol and stigmasterol have anti-proliferative activity on human lung cancer cell lines.

Targets:

NF-kB | HIF | VEGFR

In vitro:

Molecules. 2010 Apr 22;15(4):2911-24.

Organic extractives from Mentha spp. honey and the bee-stomach: methyl syringate, vomifoliol, terpenediol I, hotrienol and other compounds.[Pubmed: 20428087]

METHODS AND RESULTS:
The GC and GC/MS analyses of the solvent organic extractive from the stomach of the bees, having collected Mentha spp. nectar, revealed the presence of methyl syringate (6.6%), terpendiol I (5.0%) and Vomifoliol (3.0%) that can be attributed to the plant origin. Other major compounds from the bee-stomach were related to the composition of cuticular waxes and less to pheromones. Organic extractives from Mentha spp. honey were obtained by solvent-free headspace solid-phase microextraction (HS-SPME) and ultrasonic solvent extraction (USE) and analyzed by GC and GC/MS. The major honey headspace compounds were hotrienol (31.1%-38.5%), 2-methoxy-4-methylphenol (0.5-6.0%), cis- and trans-linalool oxides (0.9-2.8%), linalool (1.0-3.1%) and neroloxide (0.9-1.9%). Methyl syringate was the most abundant compound (38.3-56.2%) in the honey solvent extractives followed by Vomifoliol (7.0-26.6%).
CONCLUSIONS:
Comparison of the honey organic extractives with the corresponding bee-stomach extractive indicated that methyl syringate and vomofoliol were transferred to the honey while terpendiol I was partially transformed to hotrienol in ripened honey.

Phytochemistry, 1984, 23(12):2769-71.

Metabolism of abscisic acid: Bacterial conversion to dehydrovomifoliol and vomifoliol dehydrogenase activity.[Reference: WebLink]

METHODS AND RESULTS:
A species of Corynebacterium, capable of metabolizing abscisic acid (ABA), was isolated from soil. The organism converted ABA to dehydroVomifoliol [(±)-1′-hydroxy-4′-keto-α-ionone] as the major metabolise. A cell-free extract exhibited Vomifoliol dehydrogenase activity.
CONCLUSIONS:
This suggests that Vomifoliol is most likely the immediate precursor of dehydroVomifoliol.

Vomifoliol Description

Source:	The herbs of Vitis vinifera
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Molecules. 2011 Mar 16;16(3):2507-18.

Screening of natural organic volatiles from Prunus mahaleb L. honey: coumarin and vomifoliol as nonspecific biomarkers.[Pubmed: 21407151]

METHODS AND RESULTS:
Headspace solid-phase microextraction (HS-SPME; PDMS/DVB fibre) and ultrasonic solvent extraction (USE; solvent A: pentane and diethyl ether (1:2 v/v), solvent B: dichloromethane) followed by gas chromatography and mass spectrometry (GC, GC-MS) were used for the analysis of Prunus mahaleb L. honey samples. Screening was focused toward chemical composition of natural organic volatiles to determine if it is useful as a method of determining honey-sourcing. A total of 34 compounds were identified in the headspace and 49 in the extracts that included terpenes, norisoprenoids and benzene derivatives, followed by minor percentages of aliphatic compounds and furan derivatives.
CONCLUSIONS:
High Vomifoliol percentages (10.7%-24.2%) in both extracts (dominant in solvent B) and coumarin (0.3%-2.4%) from the extracts (more abundant in solvent A) and headspace (0.9%-1.8%) were considered characteristic for P. mahaleb honey and highlighted as potential nonspecific biomarkers of the honey's botanical origin. In addition, comparison with P. mahaleb flowers, leaves, bark and wood volatiles from our previous research revealed common compounds among norisoprenoids and benzene derivatives.

Product Name	Vomifoliol
Price:
CAS No.:	23526-45-6
Catalog No.:	CFN98245
Molecular Formula:	C₁₃H₂₀O₃
Molecular Weight:	224.3 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Oil
Source:	The herbs of Vitis vinifera
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-proliferation Compound Library Precursors Compound Library Sesquiterpenoids Compound Library VEGFR Inhibitor Library NF-kB Inhibitor Library HIF Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.4583 mL	22.2916 mL	44.5831 mL	89.1663 mL	111.4579 mL
5 mM	0.8917 mL	4.4583 mL	8.9166 mL	17.8333 mL	22.2916 mL
10 mM	0.4458 mL	2.2292 mL	4.4583 mL	8.9166 mL	11.1458 mL
50 mM	0.0892 mL	0.4458 mL	0.8917 mL	1.7833 mL	2.2292 mL
100 mM	0.0446 mL	0.2229 mL	0.4458 mL	0.8917 mL	1.1146 mL

CFN99871	Byzantionoside B	189109-45-3	372.5	C₁₉H₃₂O₇
CFN89279	Dehydrovomifoliol	39763-33-2	222.28	C₁₃H₁₈O₃
CFN89022	Boscialin	129277-03-8	226.31	C₁₃H₂₂O₃
CFN89291	Glochidionionol C	N/A	224.30	C₁₃H₂₀O₃
CFN98245	Vomifoliol	23526-45-6	224.3	C₁₃H₂₀O₃
CFN98916	Roseoside	54835-70-0	386.4	C₁₉H₃₀O₈
CFN99877	Corchoionol C	189351-15-3	224.3	C₁₃H₂₀O₃
CFN99859	Corchoionoside C	185414-25-9	386.4	C₁₉H₃₀O₈
CFN90997	7-Z-Trifostigmanoside I	1018898-17-3	518.55	C₂₄H₃₈O₁₂
CFN98232	9-Epiblumenol B	22841-42-5	226.3	C₁₃H₂₂O₃