Raucaffricine | CAS:31282-07-2 | Manufacturer ChemFaces

Raucaffricine

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Raucaffricine Description

Source:	The roots of Rauvolfia serpentina
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Enzyme Inhib Med Chem. 2015 Jun;30(3):472-8.

Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours.[Pubmed: 25140865]

METHODS AND RESULTS:
Insight into the structure and inhibition mechanism of O-β-d-glucosidases by deoxa-pyranosylamine type inhibitors is provided by X-ray analysis of complexes between Raucaffricine and strictosidine glucosidases and N-(cyclohexylmethyl)-, N-(cyclohexyl)- and N-(bromobenzyl)-β-d-gluco-1,5-deoxa-pyranosylamine. All inhibitors anchored exclusively in the catalytic active site by competition with appropriate enzyme substrates.
CONCLUSIONS:
Thus facilitated prospective elucidation of the binding networks with residues located at <3.9 Å distance will enable the development of potent inhibitors suitable for the production of valuable alkaloid glucosides, Raucaffricine and strictosidine, by means of synthesis in Rauvolfia serpentina cell suspension cultures.

Product Name	Raucaffricine
Price:
CAS No.:	31282-07-2
Catalog No.:	CFN97762
Molecular Formula:	C₂₇H₃₂N₂O₈
Molecular Weight:	512.56 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The roots of Rauvolfia serpentina
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.951 mL	9.755 mL	19.5099 mL	39.0198 mL	48.7748 mL
5 mM	0.3902 mL	1.951 mL	3.902 mL	7.804 mL	9.755 mL
10 mM	0.1951 mL	0.9755 mL	1.951 mL	3.902 mL	4.8775 mL
50 mM	0.039 mL	0.1951 mL	0.3902 mL	0.7804 mL	0.9755 mL
100 mM	0.0195 mL	0.0975 mL	0.1951 mL	0.3902 mL	0.4877 mL

CFN92504	Rauvomitin	466-57-9	502.6	C₃₀H₃₄N₂O₅
CFN96749	Rauvotetraphylline D	1422506-52-2	390.48	C₂₄H₂₆N₂O₃
CFN97757	Vinorine	34020-07-0	334.42	C₂₁H₂₂N₂O₂
CFN97910	Alstoyunine E	1188932-15-1	350.4	C₂₁H₂₂N₂O₃
CFN97762	Raucaffricine	31282-07-2	512.56	C₂₇H₃₂N₂O₈
CFN98673	Perakine	4382-56-3	350.4	C₂₁H₂₂N₂O₃
CFN92509	(+)-Isoajmaline	6989-79-3	326.4	C₂₀H₂₆N₂O₂
CFN93513	Ajmaline	4360-12-7	326.4	C₂₀H₂₆N₂O₂
CFN92581	Ajmalidine	639-30-5	324.4	C₂₀H₂₄N₂O₂
CFN92611	Ajmalan-17-one	3911-19-1	322.4	C₂₀H₂₂N₂O₂