Retusamine | CAS:6883-16-5 | Manufacturer ChemFaces

Retusamine

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Retusamine is a natural product from Crotalaria pallida.

In vitro:

Chem Biol Interact. 1976 Mar;12(3-4):299-324.

Hepato- and pneumotoxicity of pyrrolizidine alkaloids and derivatives in relation to molecular structure.[Pubmed: 1253333]

METHODS AND RESULTS:
The following compounds are readily converted by rat liver microsomes in vitro into dehydroheliotridine (or dehydroretronecine): 7- and 9-angelyheliotridine, 7- and 9-angelylretronecine, 7,9-dipivalylheliotridine and otosenine. 7,9-Divalerylheliotridine, the alpha- and beta-epoxides of monocrotaline, and Retusamine yield pyrrolic metabolites more slowly. The preparation and characterisation of several alkaloid derivatives are described. Chronic lung lesions were produced by most compounds which gave chronic liver lesions, although a higher dose was required in some instances.
CONCLUSIONS:
This requirement may sometimes mean that chronic lung lesions cannot be induced because of the intervention of acute or peracute deaths. Apart from this factor, structure activity requirements for pneumotoxicity are the same as for hepatotoxicity, consistent with their being both caused by the same toxic metabolites.

Retusamine Description

Source:	The herbs of Crotalaria pallida
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Retusamine
Price:
CAS No.:	6883-16-5
Catalog No.:	CFN00410
Molecular Formula:	C₁₉H₂₅NO₇
Molecular Weight:	379.41 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Crotalaria pallida
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.6357 mL	13.1784 mL	26.3567 mL	52.7134 mL	65.8918 mL
5 mM	0.5271 mL	2.6357 mL	5.2713 mL	10.5427 mL	13.1784 mL
10 mM	0.2636 mL	1.3178 mL	2.6357 mL	5.2713 mL	6.5892 mL
50 mM	0.0527 mL	0.2636 mL	0.5271 mL	1.0543 mL	1.3178 mL
100 mM	0.0264 mL	0.1318 mL	0.2636 mL	0.5271 mL	0.6589 mL

CFN00472	Senecivernine N-oxide	101687-28-9	351.4	C₁₈H₂₅NO₆
CFN00360	Cronaburmine	71295-32-4	323.39	C₁₇H₂₅NO₅
CFN00366	Crotananine	71295-28-8	323.39	C₁₇H₂₅NO₅
CFN00372	Grantianine	633-10-3	365.38	C₁₈H₂₃NO₇
CFN00387	Nemorensine	50906-96-2	337.41	C₁₈H₂₇NO₅
CFN00406	Pterophorine	62786-99-6	389.40	C₂₀H₂₃NO₇
CFN00410	Retusamine	6883-16-5	379.41	C₁₉H₂₅NO₇
CFN00414	Sceleratine	6190-25-6	369.41	C₁₈H₂₇NO₇
CFN00471	Sceleratine N-oxide	103184-92-5	385.4	C₁₈H₂₇NO₈
CFN00423	Senecivernine	72755-25-0	335.40	C₁₈H₂₅NO₅