Rosin | CAS:85026-55-7 | Manufacturer ChemFaces

Rosin

ChemFaces products have been cited in many studies from excellent and top scientific journals

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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $99.2 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Rosin may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.Rosin may cause allergic contact dermatitis in eyeshadow and mascara.

Targets:

p38MAPK | pJNK

In vitro:

Cutis,1988, 42(6):507-8.

Allergic contact dermatitis due to rosin (colophony) in eyeshadow and mascara[Pubmed: 3229138]

Three patients are reported with allergic reactions to Rosin in eye makeup: two to eyeshadow and one to mascara. In each instance, the dermatitis was bilateral and symmetrical. Several popular eyeshadow and mascara preparations contain Rosin, while the Almay products are free of this ingredient. Rosin-sensitive patients should be instructed to read cosmetic ingredient labels before using any product and should realize that the European term "colophony" is a synonym for Rosin. The numerous products that Rosin-sensitive persons must avoid will be discussed in a future article.

In vivo:

Evid Based Complement Alternat Med. 2013;2013:514049.

Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.[Pubmed: 23690847 ]

METHODS AND RESULTS:
To determine the biological activity of Rhodiola rosea, the protein expression of iNOS and proinflammatory cytokines was measured after the activation of murine microglial BV2 cells by LPS under the exposure of constituents of Rhodiola rosea: crude extract, Rosin, Rosarin, and salidroside (each 1-50 μ g/mL). The LPS-induced expression of iNOS and cytokines in BV2 cells was suppressed by the constituents of Rhodiola rosea in a concentration-dependent manner. Also the expression of the proinflammatory factors iNOS, IL-1 β , and TNF- α in the kidney and prefrontal cortex of brain in mice was suppressed by the oral administration of Rhodiola rosea crude extract (500 mg/kg). To determine the neuroprotective effect of constituents of Rhodiola rosea, neuronal cells were activated by L-glutamate, and neurotoxicity was analyzed. The L-glutamate-induced neurotoxicity was suppressed by the treatment with Rosin but not by Rosarin. The level of phosphorylated MAPK, pJNK, and pp38 was increased by L-glutamate treatment but decreased by the treatment with Rosin and salidroside.
CONCLUSIONS:
These results indicate that Rhodiola rosea may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.

Rosin Description

Source:	The herbs of Rhodiola rosea L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Rosin
Price:	$268 / 10mg
CAS No.:	85026-55-7
Catalog No.:	CFN99180
Molecular Formula:	C₁₅H₂₀O₆
Molecular Weight:	296.32 g/mol
Purity:	>=98%
Type of Compound:	Phenylpropanoids
Physical Desc.:	Powder
Source:	The herbs of Rhodiola rosea L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Proinflammatory components Compound Library Phenylpropanoids Compound Library p38MAPK Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.3747 mL	16.8737 mL	33.7473 mL	67.4946 mL	84.3683 mL
5 mM	0.6749 mL	3.3747 mL	6.7495 mL	13.4989 mL	16.8737 mL
10 mM	0.3375 mL	1.6874 mL	3.3747 mL	6.7495 mL	8.4368 mL
50 mM	0.0675 mL	0.3375 mL	0.6749 mL	1.3499 mL	1.6874 mL
100 mM	0.0337 mL	0.1687 mL	0.3375 mL	0.6749 mL	0.8437 mL

CFN95040	Cordifolioside A	155179-20-7	504.5	C₂₂H₃₂O₁₃
CFN95108	Tangshenoside I	117278-74-7	678.6	C₂₉H₄₂O₁₈
CFN99648	Sinapaldehyde glucoside	154461-65-1	370.4	C₁₇H₂₂O₉
CFN99178	Rosarin	84954-93-8	428.43	C₂₀H₂₈O₁₀
CFN90642	Forsythoside E	93675-88-8	462.44	C₂₀H₃₀O₁₂
CFN95651	2-Phenylethyl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside	239795-38-1	446.5	C₂₀H₃₀O₁₁
CFN95015	Verbasoside	61548-34-3	462.5	C₂₀H₃₀O₁₂
CFN95754	Kankanoside F	916650-12-9	624.6	C₂₆H₄₀O₁₇
CFN95741	Cistanoside E	97400-08-3	476.5	C₂₁H₃₂O₁₂
CFN95336	Peiioside B	1610618-91-1	594.6	C₂₅H₃₈O₁₆