Spiramine A | CAS:114531-28-1 | Manufacturer ChemFaces

Spiramine A

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Description:

Standard reference

In vitro:

J Nat Prod. 2009 Apr;72(4):645-9.

Approach to the biosynthesis of atisine-type diterpenoid alkaloids.[Pubmed: 19275222]

METHODS AND RESULTS:
To determine the biosynthesis pathway of the atisine-type diterpenoid alkaloids Spiramine A/B and C/D, feeding experiments in in vitro cultured plantlets and enzymatic transformations in cell-free extracts were performed in combination with LCMS and tandem MS analyses. L-[2-(13)C,(15)N]Serine was used in the feeding experiments and enzymatic transformations, and the diterpene spiraminol was identified as a biosynthetic precursor of Spiramine Alkaloids. The LCMS and tandem MS spectra of the extracts from these experiments indicated that L-[2-(13)C,(15)N]serine was incorporated into Spiramine A/B and C/D.
CONCLUSIONS:
The labeled reaction products show that l-serine is the one possible nitrogen source involved in the biosynthesis of atisine-type DAs.

Spiramine A Description

Source:	The herbs of Spiraea japonica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Spiramine A
Price:
CAS No.:	114531-28-1
Catalog No.:	CFN99243
Molecular Formula:	C₂₄H₃₃NO₄
Molecular Weight:	399.5 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Spiraea japonica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5031 mL	12.5156 mL	25.0313 mL	50.0626 mL	62.5782 mL
5 mM	0.5006 mL	2.5031 mL	5.0063 mL	10.0125 mL	12.5156 mL
10 mM	0.2503 mL	1.2516 mL	2.5031 mL	5.0063 mL	6.2578 mL
50 mM	0.0501 mL	0.2503 mL	0.5006 mL	1.0013 mL	1.2516 mL
100 mM	0.025 mL	0.1252 mL	0.2503 mL	0.5006 mL	0.6258 mL

CFN96214	Songoramine	23179-78-4	355.5	C₂₂H₂₉NO₃
CFN98058	Spiradine F	21040-64-2	399.5	C₂₄H₃₃NO₄
CFN99243	Spiramine A	114531-28-1	399.5	C₂₄H₃₃NO₄
CFN90228	Bullatine A	1354-84-3	343.51	C₂₂H₃₃NO₂
CFN93074	Karacoline	39089-30-0	377.52	C₂₂H₃₅NO₄
CFN91495	Guan-fu base A	1394-48-5	429.5	C₂₄H₃₁NO₆
CFN89550	Delgrandine	145237-05-4	741.77	C₄₁H₄₃NO₁₂
CFN89547	14-Dehydrodelcosine	1361-18-8	451.55	C₂₄H₃₇NO₇
CFN99502	Acoforestinine	110011-77-3	645.79	C₃₅H₅₁NO₁₀
CFN89329	8-Deacetylyunaconitine	93460-55-0	617.73	C₃₃H₄₇NO₁₀