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Thesinine
Thesinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Thesinine
Price:
CAS No.: 488-02-8
Catalog No.: CFN00278
Molecular Formula: C17H21NO3
Molecular Weight: 287.36 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Lithospermum erythrorhizon
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Thesinine Description
Source: The herbs of Lithospermum erythrorhizon
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.48 mL 17.3998 mL 34.7996 mL 69.5991 mL 86.9989 mL
5 mM 0.696 mL 3.48 mL 6.9599 mL 13.9198 mL 17.3998 mL
10 mM 0.348 mL 1.74 mL 3.48 mL 6.9599 mL 8.6999 mL
50 mM 0.0696 mL 0.348 mL 0.696 mL 1.392 mL 1.74 mL
100 mM 0.0348 mL 0.174 mL 0.348 mL 0.696 mL 0.87 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Frontiers in Plant Science, 2017, 8:2046.
Variability of Pyrrolizidine Alkaloid Occurrence in Species of the Grass Subfamily Pooideae (Poaceae).[Reference: WebLink]
Pyrrolizidine alkaloids (PAs) are a class of secondary metabolites found in various unrelated angiosperm lineages including cool-season grasses (Poaceae, subfamily Pooideae).
METHODS AND RESULTS:
Thesinine conjugates, saturated forms of PA that are regarded as non-toxic, have been described to occur in the two grass speciesLolium perenneandFestuca arundinacea(Poaceae, subfamily Pooideae). In a wider screen, we tested various species of the Pooideae lineage, grown under controlled conditions, for their ability to produce Thesinine conjugates or related structures. Using an LC-MS based targeted metabolomics approach we were able to show that PA biosynthesis in grasses is limited to a group of very closely related Pooideae species that produce a limited diversity of PA structures. High variability in PA levels was observed even between individuals of the same species.
CONCLUSIONS:
These individual accumulation patterns are discussed with respect to a possible function and evolution of this type of alkaloid.
Lonicerin

Catalog No: CFN95055
CAS No: 25694-72-8
Price: $168/10mg
Taurine

Catalog No: CFN00020
CAS No: 107-35-7
Price: $ /
Ganoderiol F

Catalog No: CFN99244
CAS No: 114567-47-4
Price: $398/5mg
(-)-Bilobalide

Catalog No: CFN99789
CAS No: 33570-04-6
Price: $40/20mg
Hyperoside

Catalog No: CFN98754
CAS No: 482-36-0
Price: $50/20mg
Alisol C

Catalog No: CFN92545
CAS No: 30489-27-1
Price: $318/5mg
Falcarindiol

Catalog No: CFN98220
CAS No: 225110-25-8
Price: $118/20mg
Ginsenoside Rk2

Catalog No: CFN92818
CAS No: 364779-14-6
Price: $268/5mg
Dehydromiltirone

Catalog No: CFN98532
CAS No: 116064-77-8
Price: $438/5mg
Acacetin

Catalog No: CFN98744
CAS No: 480-44-4
Price: $30/20mg
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