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Trachelosiaside
Trachelosiaside
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Trachelosiaside
Price:
CAS No.: 106647-12-5
Catalog No.: CFN89466
Molecular Formula: C26H32O11
Molecular Weight: 520.52 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The leaves of Trachelospermum lucidum (D. Don) Schum.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Trachelosiaside shows moderate activity against lipoxygenase.
In vitro:
Zeitschrift Für Naturforschung B, 2005, 60(12):1287-1290.
Isolation of a New Lipoxygenase Active Saponin and a New Triterpenoid from the Leaves of Trachelospermum lucidum[Reference: WebLink]

METHODS AND RESULTS:
A new saponin trivially named leucioside (1) and a new triterpenoid along with two known lignans Trachelosiaside (3) and matairesionol (4) C-glycosides, were isolated from the butanolic fraction of Trachelospermum lucidum.
CONCLUSIONS:
Compounds 1 and 4 showed potent inhibitory activity against lipoxyge-nase while compounds 2 and 3 showed moderate activity against lipoxygenase.
Trachelosiaside Description
Source: The leaves of Trachelospermum lucidum (D. Don) Schum.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9212 mL 9.6058 mL 19.2116 mL 38.4231 mL 48.0289 mL
5 mM 0.3842 mL 1.9212 mL 3.8423 mL 7.6846 mL 9.6058 mL
10 mM 0.1921 mL 0.9606 mL 1.9212 mL 3.8423 mL 4.8029 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7685 mL 0.9606 mL
100 mM 0.0192 mL 0.0961 mL 0.1921 mL 0.3842 mL 0.4803 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. 2008 Mar-Apr;10(3-4):317-22.
Two new lignan glycosides from Trachelospermum lucidum (D. Don) Schum.[Pubmed: 18348054]

METHODS AND RESULTS:
Two new lignans (1 and 2) having a diarylhydroxybutyrolactone skeleton were isolated from the leaves of Trachelospermum lucidum (D. Don) Schum. Their structures were elucidated to be apocynotrachelolegnin 5'-O-beta-d-glucopyranoside (1) and rafanotrachelogenin 4-O-beta-d-glucopyranoside (2) on the basis of spectroscopic analysis.
CONCLUSIONS:
Two known lignans, matairesionoside-4-O-beta-d-glucoside (3) and Trachelosiaside (4), were also isolated from Trachelospermum lucidum.
CFN96714(+)-Nortrachelogenin61521-74-2374.38C20H22O7
CFN89300(7R)-Methoxy-8-epi-matairesinol198827-23-5388.41C21H24O7
CFN90598Trachelogenin34209-69-3388.15C21H24O7
CFN93080Nortracheloside33464-78-7536.53C26H32O12
CFN90597Tracheloside33464-71-0550.2C27H34O12
CFN95235Trachelogenin 4'-O-beta-gentiobioside106647-13-6712.7C33H44O17
CFN95234Nortrachelogenin-8'-O-beta-glucoside858127-38-5536.5C26H32O12
CFN95251Nortrachelogenin-5'-C-beta-glucoside858127-39-6536.5C26H32O12
CFN96608Traxillaside149415-62-3564.59C28H36O12
CFN89466Trachelosiaside106647-12-5520.52C26H32O11
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