Structure Identification: |
Phytochemistry (Oxford), 1997, 46(3):535-543. | Di- and triterpenoids from Tripterygium hypoglaucum.[Reference: WebLink] | METHODS AND RESULTS:
The methanol extract of dried root outer bark of Tripterygium hypoglaucum (Levl.) Hutch afforded five new triterpenes: 2,3-seco-2,24-epoxy-D:A-friedoolenane-2, 24-olide-29-oic acid named celastolide, 2,23-dihydroxy-3-methoxy-6-oxo-1,3,5(10), 8-tetraene-24-nor-D:A-friedoolenane-29-oic acid, 2-hydroxy-3-methoxy-6-oxo-1,3,5(10), 8-tetraene-24-nor-D:A-friedoolenane-29-oic acid, 2,3-dihydroxy-1,3,5(10), 8-tetraene-24-nor-D:A-friedoolenane-29-oic acid and 3β,11α-dihydroxy-13(18)-ene-oleanane named triptohypol A, B and C and hypodiol, and two new diterpenes: 3β,14,19-trihydroxy-abieta-8,11,13-triene and 7-oxo-11,13-dihydroxy-19(4-3)-abeo-abieta-3,8,11,13-tetraene-19,18-olide named triptobenzene J and K, and 18 known compounds.
CONCLUSIONS:
Their structures were established on the basis of chemical and spectroscopic studies. |
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