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Uzarigenin
Uzarigenin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Uzarigenin
Price:
CAS No.: 466-09-1
Catalog No.: CFN98697
Molecular Formula: C23H34O4
Molecular Weight: 374.5 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The roots of Calotropis gigantea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Uzarigenin has cardiotonic activities.
Uzarigenin Description
Source: The roots of Calotropis gigantea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6702 mL 13.3511 mL 26.7023 mL 53.4045 mL 66.7557 mL
5 mM 0.534 mL 2.6702 mL 5.3405 mL 10.6809 mL 13.3511 mL
10 mM 0.267 mL 1.3351 mL 2.6702 mL 5.3405 mL 6.6756 mL
50 mM 0.0534 mL 0.267 mL 0.534 mL 1.0681 mL 1.3351 mL
100 mM 0.0267 mL 0.1335 mL 0.267 mL 0.534 mL 0.6676 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Experientia, 1968, 24(5):466-7.
Cardiotonic activities of 4 new compounds derived from digitoxigenin and uzarigenin, and their structure-activity relationship.[Pubmed: 5674987]

METHODS AND RESULTS:
Cardiotonic activities of 4 new compounds derived from digitoxigenin and Uzarigenin, and their structure-activity relationship.
CFN98697Uzarigenin466-09-1374.5 C23H34O4
CFN98389beta-Anhydrouzarigenin3080-20-4356.5 C23H32O3
CFN990698-Hydroxydigitoxigenin1049674-06-7390.5 C23H34O5
CFN90514Periplogenin514-39-6390.51C23H34O5
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