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Veratrosine
Veratrosine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Veratrosine
Price:
CAS No.: 475-00-3
Catalog No.: CFN93067
Molecular Formula: C33H49NO7
Molecular Weight: 571.75 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Veratrum nigrum L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vivo:
Phytother Res. 2010 Jun;24(6):821-6.
Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum.[Pubmed: 20013819 ]
Ten steroidal alkaloids - cyclopamine, veratramine, jervine, 3, 15-diangyloylgermine, 3-angyloylzygadenine, 3-veratroyl zygadenine, 15-veratroylgermine, germine, Veratrosine and pseudojervine - from Veratrum dahuricum, together with the ethanol extract and total alkaloids, were evaluated for their antitumor and antiplatelet activities.
METHODS AND RESULTS:
Cyclopamine, veratramine and germine significantly inhibited the hedgehog pathway in NIH/3T3 cells. Cyclopamine exerted a potent inhibitory effect against the growth of PANC-1 tumors in mice, with inhibition rates of 40.64%, 44.37%, 46.77% at doses of 5.0, 15.0 and 50.0 mg kg-1, respectively. Veratroylgermine was found to produce the strongest inhibition against the platelet aggregation induced by arachidonic acid, with inhibition rate of 92.0% at 100 microM.
Veratrosine Description
Source: The herbs of Veratrum nigrum L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.749 mL 8.7451 mL 17.4902 mL 34.9803 mL 43.7254 mL
5 mM 0.3498 mL 1.749 mL 3.498 mL 6.9961 mL 8.7451 mL
10 mM 0.1749 mL 0.8745 mL 1.749 mL 3.498 mL 4.3725 mL
50 mM 0.035 mL 0.1749 mL 0.3498 mL 0.6996 mL 0.8745 mL
100 mM 0.0175 mL 0.0875 mL 0.1749 mL 0.3498 mL 0.4373 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Coelonin

Catalog No: CFN92693
CAS No: 82344-82-9
Price: $388/5mg
Cordifolioside A

Catalog No: CFN95040
CAS No: 155179-20-7
Price: $318/10mg
Genkwanin

Catalog No: CFN98670
CAS No: 437-64-9
Price: $60/20mg
Crategolic acid

Catalog No: CFN98669
CAS No: 4373-41-5
Price: $80/20mg
Malvidin-3-O-glucoside chloride

Catalog No: CFN92049
CAS No: 7228-78-6
Price: $238/10mg
Damulin B

Catalog No: CFN91837
CAS No: 1202868-75-4
Price: $288/5mg
Curculigoside

Catalog No: CFN97419
CAS No: 85643-19-2
Price: $70/20mg
Quercitrin

Catalog No: CFN98850
CAS No: 522-12-3
Price: $40/20mg
Stearic Acid

Catalog No: CFN93165
CAS No: 57-11-4
Price: $30/20mg
Silydianin

Catalog No: CFN90242
CAS No: 29782-68-1
Price: $168/20mg
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