ent-16-Kaurene-3beta,15beta,18-triol | CAS:921211-29-2

ent-16-Kaurene-3beta,15beta,18-triol

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Description:

ent-16-Kaurene-3beta,15beta,18-triol, ent-16-kaurene-3beta,15beta-diol,abbeokutone,and helioscopinolide A possess appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.

In vitro:

Phytochemistry. 2006 Dec;67(24):2630-4.

Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora.[Pubmed: 17095024 ]

METHODS AND RESULTS:
Two ent-kaurene diterpenes, ent-16-Kaurene-3beta,15beta,18-triol (1) and ent-3-oxo-16-kaurene-15beta,18-diol (2), were isolated from a dichloromethane extract of the bark of Suregada multiflora along with five known diterpenes:ent-16-kaurene-3beta,15beta-diol (3), abbeokutone (4), helioscopinolide A (5), helioscopinolide C (6) and helioscopinolide I (7). Their structures were elucidated on the basis of spectroscopic analysis.
CONCLUSIONS:
Compounds 1-7 possessed appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM.

ent-16-Kaurene-3beta,15beta,18-triol Description

Source:	The barks of Suregada multiflora.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	ent-16-Kaurene-3beta,15beta,18-triol
Price:
CAS No.:	921211-29-2
Catalog No.:	CFN96331
Molecular Formula:	C₂₀H₃₂O₃
Molecular Weight:	320.5 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The barks of Suregada multiflora.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-allergy Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1201 mL	15.6006 mL	31.2012 mL	62.4025 mL	78.0031 mL
5 mM	0.624 mL	3.1201 mL	6.2402 mL	12.4805 mL	15.6006 mL
10 mM	0.312 mL	1.5601 mL	3.1201 mL	6.2402 mL	7.8003 mL
50 mM	0.0624 mL	0.312 mL	0.624 mL	1.248 mL	1.5601 mL
100 mM	0.0312 mL	0.156 mL	0.312 mL	0.624 mL	0.78 mL

CFN98977	11,15-Dihydroxy-16-kauren-19-oic acid	57719-76-3	334.5	C₂₀H₃₀O₄
CFN97261	ent-9-Hydroxy-15-oxo-16-kauren-19-oic acid	77658-39-0	332.4	C₂₀H₂₈O₄
CFN97294	ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid	81264-00-8	348.4	C₂₀H₂₈O₅
CFN89107	ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide	59885-89-1	346.42	C₂₀H₂₆O₅
CFN97975	Pterisolic acid A	1401419-85-9	346.4	C₂₀H₂₆O₅
CFN97976	Pterisolic acid B	1401419-86-0	330.4	C₂₀H₂₆O₄
CFN89078	ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid	57719-81-0	332.44	C₂₀H₂₈O₄
CFN89216	Paniculoside III	60129-65-9	494.58	C₂₆H₃₈O₉
CFN96331	ent-16-Kaurene-3beta,15beta,18-triol	921211-29-2	320.5	C₂₀H₃₂O₃
CFN97780	Grandifloric acid	22338-69-8	318.46	C₂₀H₃₀O₃