Hot Products
Catalog No. | Information |
CFN98701 | Cycloeucalenol Cycloeucalenol produces mild cardiotonic effects. Cycloeucalenol and its regio-isomer were present in a ratio of 1.04:1, a dose-dependent decrease in cell viability was observed. |
CFN97714 | Cyclomorusin Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophils. Cyclomorusin , neocyclomorusin and kuwanon C inhibited cholinesterase enzyme in a dose-dependent manner with K(i) values ranging between 3.1 and 37.5 uM and between 1.7 and 19.1 uM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively. |
CFN92417 | Cyclomulberrin Cyclomulberrin shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation, it also shows slight but significant antiplatelet effects on the aggregation induced by PAF. Cyclomulberrin enhances cell viability in a dose-dependent manner against sodium nitroprusside-induced cell death in neuroblastoma SH-SY5Y cells. It exhibits potent inhibition of human PLC/PRF/5 and KB cells in-vitro. |
CFN96185 | Cycloolivil (+)-Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies. |
CFN90928 | Cyclopamine Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay, it can increase levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells. Cyclopamine as a novel, potent inhibitor of human breast cancer proliferation and estrogen responsiveness that could potentially be developed into a promising therapeutic agent for the treatment of breast cancer. Cyclopamine also can suppress the growth of leukemia and lymphoma cells. |
CFN93169 | Cyclopentadecanone Used in perfumery (musk odour). |
CFN60180 | Cyclosporin A |
CFN99176 | Cyclovirobuxine Cyclovirobuxine D(CVB-D) has vasorelaxant effect, it has been widely used for treatment of cardiac insufficiency and arrhythmias in China, the antiarrhythmic and proarrhythmic potential of this drug might be concerned with prolongation of action potential duration and QT interval. CVB-D can induce autophagy in the MCF-7 human breast cancer cell line by attenuating the phosphorylation of Akt and mTOR , CVB-D-induced autophagy and decrease in cell viability could be blocked by 3-methyladenine, a well-established autophagy inhibitor. |
CFN70386 | Cymarin Cymarin exhibits potent cytotoxicity against a human solid tumor cell line A549 (human lung carcinoma), while being inactive on murine leukemic cells (L1210). |
CFN96784 | Cynatratoside A Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis. |