Curcolonol | CAS:217817-09-9 | Manufacturer ChemFaces

Curcolonol

ChemFaces products have been cited in many studies from excellent and top scientific journals

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Standard reference

In vitro:

J Nat Prod. 1998 Dec;61(12):1531-4.

Cytotoxicity of curcuminoids and some novel compounds from Curcuma zedoaria.[Pubmed: 9868158]

METHODS AND RESULTS:
Bioassay-directed fractionation of an EtOH extract of Curcuma zedoaria led to isolation of an active curcuminoid, which was identified as demethoxycurcumin (2) by comparison of its 1H and 13C NMR spectra with literature data and by direct comparison with synthetic material. Curcumin (1) and bisdemethoxycurcumin (3) were also obtained. Curcuminoids (1-3) were synthesized and demonstrated to be cytotoxic against human ovarian cancer OVCAR-3 cells.
CONCLUSIONS:
The observed CD50 values of 1, 2, and 3 were 4.4, 3.8, and 3.1 microg/mL, respectively. Three additional novel compounds, 3, 7-dimethylindan-5-carboxylic acid (4), Curcolonol (5), and guaidiol (6), were also isolated from the EtOH extract. The structures and relative stereochemistry of 4-6 were determined by spectroscopic methods and X-ray crystallographic analysis.

Curcolonol Description

Source:	The rhizomes of Curcuma zedoaria
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Yao Xue Xue Bao. 2005 Jun;40(6):525-8.

Studies on the chemical constituents from the roots of Chloranthus henryi.[Pubmed: 16144317]

To study the chemical constituents of the roots of Chloranthus henryi.
METHODS AND RESULTS:
The constituents of Chloranthus henryi were separated with various chromatographic techniques. structures were elucidated by physico-chemical properties and spectral data. Eight compounds were isolated from Chloranthus henryi. They were identified as Curcolonol (I), zedoarofuran (II), shizukanolide E (III) , skimmin (IV), calucanthoside (V), chloracoumarin (VI), beta-sitosterol (VII), daucosterin (VIII).
CONCLUSIONS:
Chloracoumarin (VI) is a new compound and characterized as 6,8-dimethoxy-7-O-[beta-D-apiofunanosyl(l --> 3 )-D-glucopyranosyl]-2H-benzopyran-2-one. Compounds I, II were isolated from Chloranthus henryi for the first time.

Product Name	Curcolonol
Price:
CAS No.:	217817-09-9
Catalog No.:	CFN92650
Molecular Formula:	C₁₅H₂₀O₄
Molecular Weight:	264.3 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Powder
Source:	The rhizomes of Curcuma zedoaria
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.7836 mL	18.9179 mL	37.8358 mL	75.6716 mL	94.5895 mL
5 mM	0.7567 mL	3.7836 mL	7.5672 mL	15.1343 mL	18.9179 mL
10 mM	0.3784 mL	1.8918 mL	3.7836 mL	7.5672 mL	9.4589 mL
50 mM	0.0757 mL	0.3784 mL	0.7567 mL	1.5134 mL	1.8918 mL
100 mM	0.0378 mL	0.1892 mL	0.3784 mL	0.7567 mL	0.9459 mL

CFN91948	8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide	956707-04-3	262.30	C₁₅H₁₈O₄
CFN92651	Curcolone	17015-43-9	246.3	C₁₅H₁₈O₃
CFN92619	Zedoarofuran	213833-34-2	264.3	C₁₅H₂₀O₄
CFN92650	Curcolonol	217817-09-9	264.3	C₁₅H₂₀O₄
CFN89321	1beta,10beta-Epoxy-6beta-isobutyryloxy-9-oxofuranoeremophilane	59742-11-9	332.39	C₁₉H₂₄O₅
CFN89320	6beta-Angeloyloxy-1beta,10beta-epoxy-9-oxofuranoeremophilane	59780-08-4	344.40	C₂₀H₂₄O₅
CFN92027	Curzerenone	20493-56-5	230.3	C₁₅H₁₈O₂
CFN92613	Epicurzerenone	20085-85-2	230.3	C₁₅H₁₈O₂
CFN99762	Isolinderalactone	957-66-4	244.29	C₁₅H₁₆O₃
CFN92066	Atractylone	6989-21-5	216.3	C₁₅H₂₀O