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Natural Products
Catalog No. Information
CFN91055 Dihydrowithaferin A

2, 3-Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors in human.
CFN70059 Dihydroxyfumaric acid

Dihydroxyfumaric acid can induce lipid peroxidation in rat liver microsomes.
CFN99853 Dimeric coniferyl acetate

Dimeric coniferyl acetate has anti-inflammary activity, it shows strong NO inhibition with IC50 values of 27.1 uM in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. It exhibits significant inhibitory effects on the nitric oxide production in lipopolysaccharide activated C57BL6/J mouse macrophages.
CFN90690 Dimethyl lithospermate B

Dimethyl lithospermate B is a highly potent natural antioxidant and antidiabetic polyphenol with unknown mode of action.Dimethyl lithospermate B slows inactivation of INa, leading to increased inward current during the early phases of the action potential (AP), might be an excellent candidate for a Na(+) channel agonist; it is effective in eliminating the arrhythmogenic substrate responsible for the Brugada syndrome and that it deserves further study as a pharmacological adjunct to implanted cardioverter/defibrillator usage.
CFN90164 Dimethylacrylshikonin

Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors, it inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-κB pathway. Dimethylacrylshikonin inhibits agonist-induced relaxation at lower concentrations and induces vasocontraction at higher concentrations.
CFN90607 Dimethylcurcumin

Dimethylcurcumin is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion.
CFN98014 Diosbulbin B

Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time, it also exhibits potential hepatotoxicity.
CFN98015 Diosbulbin C

Diosbulbin C has hepatotoxicity.
CFN99516 Dioscin

Dioscin has anti-obesity, antineoplastic, anti-cancer, anti-inflammatory, uricosuric and nephroprotective actions, it can potentially contribute to treatments for inflammatory diseases and atherosclerosis. Dioscin clearly protected PC12 cells and primary cortical neurons against OGD/R insult and significantly prevented cerebral I/R injury. It inhibited AMPK/MAPK pathway and regulated VEGFR2 and AKT/MAPK signaling pathways.
CFN99515 Diosgenin

Diosgenin possesses antivascular calcification , anti-osteoclastogenesis, anti-inflammatory and anticancer properties, it has favorable effects in the improvement of diabetes and regulation of lipid metabolism. Diosgenin treated inflammation-related disorders through the blockade of cAMP, PKA, cPLA2, PAK, Akt and MAPKs signaling pathways. Diosgenin may decrease the risk of developing dementia of opiate abusers with HIV infection and the ApoE4 allele.