Hot Products
| Catalog No. | Information |
| CFN99798 | Deoxycholic acid Deoxycholic acid is a strong promoter of hepatocarcinogenesis with possible complete carcinogenicity in the liver and promotion potential for tumor development in the small intestine. Loss of deoxycholic acid-induced EGFR/Ras/MAPK pathway function potentiates deoxycholic acid-stimulated FAS-induced hepatocyte cell death via a reduction in the expression of c-FLIP isoforms. |
| CFN97764 | Deoxyelephantopin Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity, by inhibiting metastatic, inducing apoptosis, modulating oxidative stress , STAT3/p53/p21 signaling, MAPK pathway, PI3k/Akt/mTOR pathway, caspase cascades, and ROS . |
| CFN90484 | Deoxynojirimycin hydrochloride 1-Deoxynojirimycin hydrochloride shows inhibitory activity against α-glucosidases, inhibitors of α-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs. |
| CFN99888 | Deoxypodophyllotoxin Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities. Deoxypodophyllotoxin induces G2 /M cell-cycle arrest followed by apoptosis through multiple cellular processes, involving the activation of ATM, upregulation of p53 and Bax, activation of caspase-3 and -7, and accumulation of PTEN resulting in the inhibition of the Akt pathway. Deoxypodophyllotoxin maybe applicable to treat hyperpigmentation, it decreases UV-induced skin pigmentation of brown guinea pigs. |
| CFN92024 | Deoxyshikonin Deoxyshikonin and dodecyl gallate show significantly synergic antimicrobial activity with penicillin in vivo and in vitro, and can effectively reduce nasopharyngeal and lung colonization caused by different penicillin-resistant pneumococcal serotypes. Deoxyshikonin exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·, and shows cytotoxic activities. Deoxyshikonin may be a new drug candidate for wound healing and treatment of lymphatic diseases. |
| CFN96046 | Derrisisoflavone B Derrisisoflavone B is a natural product from Derris robusta. |
| CFN97689 | Derrone Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. It is also a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids. |
| CFN91787 | Deslanoside Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. |
| CFN90149 | Desmethoxy yangonin Desmethoxyyangonin is a reversible inhibitor of MAO-B, it may have important therapeutic value for treatment of neurodegenerative disorders and Parkinson's Disease. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. |
| CFN93532 | Desmethylbellidifolin Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method; it also exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus. Desmethylbellidifolin exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus. |
