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Natural Products
Catalog No. Information
CFN96725 Gomisin E

Gomisin E is a natural product from Schizandra chinensis.
CFN92719 Gomisin F

Standard reference
CFN90123 Gomisin G

Gomisin G is a drug candidate for treatment of cardiovascular disease, and it is a good substrate of CYP2C9, and can be easily affected by the inhibitors of CYP2C9. Gomisin G exhibits anti-tumor activities, it exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.
CFN94008 Gomisin H

Gomisin H is a natural product from Schizandra chinensis.
CFN90124 Gomisin J

Gomisin J is a good substrate of cytochrome P450 3A4(CYP3A4), it has vasodilatory, anti-inflammatory, anti-diabetes, anti-oxidant, and anti-cancer effects, it also has preventive effects on angiotensin II-induced hypertension via an increased nitric oxide bioavailability. Gomisin J has potential benefits in treating nonalcoholic fatty liver disease, it can suppress lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecule. Halogenated gomisin J is a potent inhibitor of the cytopathic effects of human immunodeficiency virus type 1 (HIV-1) on MT-4 human T cells (50% effective dose, 0.1 to 0.5 microM).
CFN96724 Gomisin K1

Gomisin K1 is a natural product from Schizandra chinensis BAILL.
CFN96734 Gomisin L1

(-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells.
CFN96726 Gomisin L2

Gomisin L2 is a natural product from Schizandra chinensis BAILL.
CFN97306 Gomisin M2

Gomisin M2 is an anti-HIV agent.
CFN90125 Gomisin N

Gomisin N has anti-oxdiant, anti-inflammatory, anti-cancer and anti-hepatitis activities; it produces beneficial sedative and hypnotic bioactivity, which may be mediated by the modification of the serotonergic and GABAergic system. Gomisin N can enhance TNF-α-induced apoptosis by suppressing of NF-κB and EGFR signaling pathways, and potentiate TRAIL-induced apoptosis through ROS-mediated up-regulation of death receptors 4 and 5.