Hot Products
| Catalog No. | Information |
| CFN91626 | Hyocholic acid Hyocholic acid(HCA) upregulates GLP-1 production and secretion in enteroendocrine cells and improves glucose homeostasis. Hyocholic acid has the effect of preventing and dissolving gallstones. |
| CFN99797 | Hyodeoxycholic acid Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells. Hyodeoxycholic acid has hypolipidemic effect through regulation of FXR activation, it is a candidate for antiatherosclerotic drug, by significantly increasing the expression of genes involved in cholesterol efflux, such as Abca1, Abcg1,and Apoe,in a macrophage cell line. |
| CFN00232 | Hyoscyamine Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM, it is widely used in medicine due to its anticholinergic activity. Hyoscyamine could be used to reduce abdominal discomfort and colonic spasm during a barium enema. |
| CFN90713 | Hyoscyamine sulfate hydrate Reference standards. |
| CFN93039 | Hypaconine Hypaconine exhibits strong cardiac activity. |
| CFN99200 | Hypaconitine Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism. It produced neuromuscular blockade by reducing the evoked quantal release, the mechanism of this effect was attributed mainly to blocking of the nerve compound action potential. |
| CFN90634 | Hypaphorine Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.Hypaphorine and endogenous indole-3-acetic acid counteract in controlling root hair elongation. |
| CFN91083 | Hyperforin Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts. Hyperforin acts as a dual inhibitor of 5-LO and COX-1 in intact cells as well as on the catalytic activity of the crude enzymes, suggesting therapeutic potential in inflammatory and allergic diseases connected to eicosanoids. |
| CFN99188 | Hypericin Hypericin is a photosensitive antiviral with anticancer and antidepressant agent . It can inhibit tyrosine kinases with IC50 of 7.5 μM. It can induce both apoptosis and necrosis in a concentration and light dose-dependent fashion, and inhibit RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo. |
| CFN98754 | Hyperoside Hyperoside, a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, neuroprotective, antifungal, hepatoprotective, anti-inflammatory and antioxidative effects. Hyperoside is a potent natural activator of Nur77 receptor, and a potent selective CYP2D6 inhibitor; it inhibited the HMGB1 signaling pathway, and inhibited the PI3K/Akt/Bad/Bcl XL -regulated mitochondrial apoptotic pathway. Hyperoside is a strong inhibitor of HBsAg and HBeAgsecretion in 2.2.15 cells and DHBV-DNA levels in the HBV-infected duck model. |
