Hot Products
Catalog No. | Information |
CFN99491 | Hispidulin Hispidulin has anti-oxidative, anti-inflammatory, anti-cancer, antiepileptic, neuroprotective, anti-osteoporotic and bone resorption attenuating effects, it targets the VEGF receptor 2-mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis. Hispidulin can ameliorate high glucose-mediated endothelial dysfunction via inhibiting PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling, it has potential application in the prevention and treatment of diabetic vascular complications. Hispidulin can inhibit platelet aggregation by elevating cAMP levels by a mechanism different from that of theophylline or PGE1. |
CFN90892 | Hispidulin 7-O-neohesperidoside Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant. |
CFN90029 | Histamine Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist. Histamine increases Nav1.8 expression in primary afferent neurons via H2 receptor-mediated pathway and thereby contributes to neuropathic pain, H2 receptor antagonists may potentially be used as analgesics for patients with neuropathic pain. |
CFN00476 | Homatropine |
CFN90539 | Homoarbutin Reference standards. |
CFN70340 | Homobutein Homobutein as a dual inhibitors of HDACs and NF-κB, it can serve as a lead compound in the development of dual inhibitors against both targets in the treatment of inflammation and cancer. Homobutein shows antioxidant and antimalarial properties based on its ability to chelate iron (II and III) cations. |
CFN90964 | Homodihydrocapsaicin I Homodihydrocapsaicin I is a natural product from Capsicum annuum L. |
CFN96489 | Homoeriodictyol Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells. |
CFN93816 | Homogentisic acid Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. Homogentisic acid shows interesting antioxidant and antiradical activities, and protective effect against thermal-cholesterol degradation. A derivative of homogentisic acid which inhibits Pfnek-1 with an IC(50) around 1.8 muM, this product is moderately active in vitro against a FcB1 P. falciparum strain (IC(50) = 12 muM). |
CFN98110 | Homoharringtonine Homoharringtonine, a plant alkaloid with antitumor and antileukemic properties, inhibit protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine might have clinical activity in some patients with myelodysplastic syndrome. |