Hydroprotopine | CAS:128397-41-1 | Manufacturer ChemFaces

Hydroprotopine

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $35.9 / In-stock
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Description:

Reference standards.

In vitro:

Journal of Separation Science, 2015, 38(23):4063-4070.

Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase.[Reference: WebLink]

METHODS AND RESULTS:
A method that involved the combination of pH-zone-refining counter-current chromatography and semipreparative reversed-phase liquid chromatography has been established for the preparative separation of alkaloids from Hypecoum leptocarpum. From 1.2 g of crude sample, 31 mg N-feruloyltyramine, 27 mg oxohydrastinine, 47 mg Hydroprotopine, 25 mg leptopidine, and 18 mg hypecocarpine have been obtained. The structure of the new compound, hypecocarpine, is confirmed based on the analysis of spectroscopic data, including NMR, UV, and IR spectroscopy and positive electrospray ionization mass spectrometry. The known chemical structures were characterized on the basis of (1) H and (13) C NMR spectroscopy. The purities of the five alkaloids are all over 92.7% as determined by high-performance liquid chromatography. The alkaloids' cytotoxicity in breast cancer cells is assessed by using a Cell Counting Kit assay and their inhibitory effect on fatty acid synthase expression is assessed by a Western blot assay.
CONCLUSIONS:
These results suggest that leptopidine could suppress growth and induce cytotoxicity in breast cancer cells and that the cytotoxicity of leptopidine may be related to its inhibitory effect on fatty acid synthase expression.

Hydroprotopine Description

Source:	The herbs of Macleaya cordata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Hydroprotopine
Price:	$168 / 20mg
CAS No.:	128397-41-1
Catalog No.:	CFN99388
Molecular Formula:	C₂₀H₂₀NO₅
Molecular Weight:	354.4 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Macleaya cordata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8217 mL	14.1084 mL	28.2167 mL	56.4334 mL	70.5418 mL
5 mM	0.5643 mL	2.8217 mL	5.6433 mL	11.2867 mL	14.1084 mL
10 mM	0.2822 mL	1.4108 mL	2.8217 mL	5.6433 mL	7.0542 mL
50 mM	0.0564 mL	0.2822 mL	0.5643 mL	1.1287 mL	1.4108 mL
100 mM	0.0282 mL	0.1411 mL	0.2822 mL	0.5643 mL	0.7054 mL

CFN98051	Mangochinine	209115-67-3	328.4	C₁₉H₂₂NO₄
CFN98254	Allocryptopine	24240-04-8	369.4	C₂₁H₂₃NO₅
CFN99143	Phellodendrine	6873-13-8	342.4	C₂₀H₂₄NO₄
CFN99144	Phellodendrine chloride	104112-82-5	377.85	C₂₀H₂₄NO₄.Cl
CFN99388	Hydroprotopine	128397-41-1	354.4	C₂₀H₂₀NO₅
CFN99399	Protopine	130-86-9	353.4	C₂₀H₁₉NO₅
CFN89127	Coulteropine	6014-62-6	383.4	C₂₁H₂₁NO₆
CFN89163	1-Methoxyallocryptopine	56743-52-3	399.44	C₂₂H₂₅NO₆