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Natural Products
Catalog No. Information
CFN00375 Jacobine

Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.
CFN00461 Jacobine N-oxide

CFN00376 Jacoline

Jacoline, jaconine, jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer.
CFN00377 Jaconine

Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer.
CFN92274 Jacoumaric acid

Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor.
CFN95434 Jacquilenin

Jacquilenin has anti-inflammatory activity
CFN98493 Jatrorrhizine

Jatrorrhizine has neuroprotective, antioxidative, anti-inflammatory, antihypercholesterolemic, and anti-hyperglycemia effects.Jatrorrhizine is expected to be developed as a new gastric prokinetic drug, it is metabolized by human CYP1A2 and multiple UGT1A isoforms. It has inhibitory activities against the expression of inducible NO syntase (iNOS) and cyclooxygenase-2 (COX-2), and can improve the utilization and excretion of cholesterol by up-regulating the mRNA and protein expression of LDLR and CYP7A1.
CFN98108 Jatrorrhizine Hydrochloride

Jatrorrhizine hydrochloride has lipid lowering effects, it can ameliorate hyperlipidemia via the suppression of lipogenesis and the enhancement of lipid oxidation in the liver. It exhibits a potent inhibitory effect toward neuraminidase of the H7N9 (N9) avian influenza virus, it also can potentiate the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza. Jatrorrhizine hydrochloride is a potential new antimelanoma drug candidate, can inhibit the proliferation and neovascularization of C8161 metastatic melanoma cells with low toxicity.
CFN90955 Jervine

Jervine exhibits cytotoxic activity against human tumor cell lines A549, PANC-1, SW1990 and NCI-H249, it induces COX-2 overexpression in human erythroleukemia cells. Jervine exhibits potent toxic effects against Colorado potato beetle.
CFN90809 Jionoside A1

Jionoside A1 displays dose dependent immune-enhancement activity and possesses moderate neuroprotective activities on H2O2-treated SH-SY5Y cells.