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Natural Products
Catalog No. Information
CFN60035 Selisistat (EX 527)

Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3.
CFN90818 Semilicoisoflavone B

Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia.
CFN97173 Sempervirine

Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA .
CFN00416 Seneciocannabine

Reference standards.
CFN00417 Senecionine

Senecionine (SEN) is a representative of the hepatotoxic pyrrolizidine alkaloids.
CFN00418 Senecionine N-oxide

Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters.
CFN98747 Seneciphylline

Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.
CFN98618 Seneciphylline N-oxide

Seneciphylline N-oxide and senecionine N-oxide are probably tumorigenic due to their potential conversion into seneciphylline and senecionine via metabolic reduction in the body.
CFN00423 Senecivernine

Reference standards.
CFN00472 Senecivernine N-oxide