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Natural Products
Catalog No. Information
CFN80061 Ptaquiloside

Ptaquiloside shows genotoxicity, it also has carcinogenic effects. Ptaquiloside has immunosuppressive effects, it reduces NK cell activities by enhancing metallothionein expression, which is prevented by selenium.
CFN97976 Pterisolic acid B

Pterisolic acid B (J19) is an effective Nrf2 activator. we have also identified a more potent natural product analogue J19-1, J19-1 shows significant cytoprotective effect against cisplatin-induced cytotoxicity in HKC cells.
CFN98614 Pterolactam

Reference standards.
CFN93247 Pteropodine

Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects, it also shows strong apoptotic effect on acute leukaemic lymphoblasts.
CFN80051 Pterosin A

Pterosin A is a novel activator of adenosine monophosphate-activated protein kinase, which is crucial for regulating blood glucose homeostasis. Pterosin A has potential anti-diabetic activity, it can significantly reverse the increased serum insulin and insulin resistance (IR) in dexamethasone-IR mice and in db/db mice.
CFN96798 Pterosin B

Pterosin B is a salt-inducible kinase 3 (Sik3) pathway inhibitor, it prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Pterosin B shows cytotoxicity against HL 60 cells (human leukemia) with the IC(50) value of 8.7 microg/mL. Pterosin B has multiple targets in gluconeogenic programs, including coenzyme Q in RORα-SRC2 signaling.
CFN96802 Pterosin C

Pterosin C is a natural product from Pteris semipinnata.
CFN98443 Pterosin D

Reference standards.
CFN80185 Pterosin G

Reference standards.
CFN98442 Pterosin Z

Pterosin Z has smooth muscle relaxant activity, is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M).