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Natural Products
Catalog No. Information
CFN98786 Savinin

Savinin has antiinflammatory effect, can significantly inhibit tumor necrosis factor (TNF)-a production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells, and T cell proliferation elicited by concanavalin (Con A), without displaying cytotoxicity. Savinin also exhibits potent spermicidal activity and significant insecticidal activity.
CFN97798 Scabertopin

Scabertopin exhibits significant antitumor effect in vitro in a concentration-dependent manner.
CFN92535 Scandoside

Scandoside exerts anti-inflammatory effect via suppressing NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages.It also inhibits LDL-oxidation.
CFN90197 Schaftoside

Schaftoside has antioxidant activity, it also can inhibit phospholipase, lipoxygenase and cyclooxygenase, three pro-inflammatory enzymes.
CFN92717 Schineolignin B

Standard reference
CFN97283 Schinifoline

Schinifoline has cytotoxic activity, it also shows in vitro radiosensitising, cell cycle and apoptotic-inducing effects.
CFN99012 Schisandrol A

Schisandrol A may be a new promising treatment for neurotoxicity, erectile dysfunction and cardiovascular disease.It can inhibit the activities of Pgp,Beta Amyloid,CYP3A4,cGMP,and NOS, the IC(50) value of CYP3A4 is 32.02 microM.
CFN92351 Schisandrone

Schisandrone has strong activities of anti-oxidation, effectively scavenges hydroxyl radical and superoxide anion, and has protective effects on cells under active oxygen stress state. Schisandrone can significantly decrease phosphorylation levels of Tau protein at 396, 262 sites, and relieve neuronal injury, but the phosphorylation level does not reach a negative cell level; it can suppress the Aβ-induced oxidative stress and inflammatory reaction through influencing NF-κB signaling pathway, exerting its protective effect on Alzheimer disease.
CFN90364 Schisanhenol

Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals; it also has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation. Schisanhenol can protect against adriamycin induced heart mitochondrial toxicity.
CFN92212 Schisanlactone A

Schisanlactone A is a dimerization inhibitor, with an IC50 value of 5.0 microg/mL; it also shows appreciable inhibitory activity against HIV-1 protease with the IC50 value of 20 microM. Schisanlactone A shows cytotoxicity against KB (a human epidermal carcinoma) cells with the IC50 value of 63.3 uM.