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Natural Products
Catalog No. Information
CFN91968 Sominone

Sominone improves memory impairments and increases axonal density in Alzheimer's disease model mice. It enhances neurite outgrowth and spatial memory mediated by the neurotrophic factor receptor, RET.
CFN95280 Somnifericin

CFN99255 Sootepin D

Sootepin D shows anti-inflammatory activity.
CFN94852 Sophocarpine

Sophocarpine has anti-cancer, anti-inflammatory, anti-nociceptive, and antivirus activities, it can prevent implant loosening through inhibiting osteoclast formation and bone resorption, thus, it may be a novel therapeutic agent to prevent prosthesis loosening and for osteolytic diseases. Sophocarpine could attenuate ConA-induced liver injury, and the protective effect of Sophocarpine was associated with its inhibition effect of pro-inflammatory cytokines, chemokines, and the IFN-γ/STAT1 signaling pathway.
CFN99182 Sophocarpine

Sophocarpine has anti-cachectic, anti-inflammatory, and neuroprotective effects. It has significant antivirus effects against coxsackievirus B3 and therapeutic effects for viral myocarditis in clinical, can ameliorate the ischemic injury induced by transient focal cerebral ischemia in rats, and may be a potential chemotherapeutic agent for chronic liver diseases. Sophocarpine inhibited the expression of TNF-alpha, IL-6, JNK, iNOS, COX-2, p38 MAPK, NF-κB, TLR4, and activated signaling pathway of AMPK.
CFN90767 Sophoflavescenol

Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells.
CFN90958 Sophorabioside

Sophorabioside is a natural product from Sophora japonica.
CFN92635 Sophoraflavanone C

Standard reference
CFN92005 Sophoraflavanone G

Sophoraflavanone G has an anti-inflammatory effect, it has strong antimicrobial activity against mutans streptococci and could be useful in the development of novel oral hygiene products, such as a gargle solution or dentifrice. Sophoraflavanone G is a novel small-molecule inhibitor, it inhibits the NF-κB and MAPK signaling pathways.
CFN90148 Sophoricoside

Sophoricoside has anti-inflammatory, anti-cancer, anti-bone loss, and immunosuppressive effects. Sophoricoside is an effective regulator of lipogenesis and glucose consumption and may find utility in the treatment of obesity and type 2 diabetes. Sophoricoside exposure reduced the number of implanted embryos in a dose-dependent manner and failed the embryo implantation through altering the morphology of uterine and compromising the endometrial receptivity.