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Catalog No. Information
CFN91713 Picrotin

Picrotin is an inhibitor of glycine receptors. Picrotin blocks α2 GlyR, α1 GlyR and α3 GlyR. Picrotin is a more potent inhibitor of GABA than glycine in retinal neurons.
CFN70291 Picrotoxinin

Picrotoxinin and bicuculline may antagonize GABA responses by stabilizing the closed form of the activated channel, whereas penicillin-G may block the channel in the open state.
Picrotoxin is an inducer of phenobarbital-inducible liver enzymes.
CFN95226 Pieceid-2''-O-gallate

Pieceid-2''-O-gallate has antioxidant activity.
CFN96503 Pilloin

Pilloin exerts a cytotoxic action targeted at the transformed lymphoblasts.
CFN70491 Pilocarpine

Pilocarpine has been used to treat glaucoma, ocular hypertension and xerostomia. Pilocarpine can induce seizures. It antagonizes prostaglandin F2 alpha-induced ocular hypotension in monkeys. the ability of oral pilocarpine to normalise and reverse the salivary biochemical and immunological alterations induced by cGVHD parallels its known stimulatory effect on salivary flow rates. The combination of pilocarpine and sorbitol has effective antimicrobial activity.
CFN93245 Pilocarpine Hydrochloride

Pilocarpine hydrochloride appears to be effective for dry mouth associated with Sjögren's syndrome. It has acaricidal activity.
CFN99382 Pimaric acid

Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells. 4-epi-Pimaric acid shows antibacterial, anti-biofilm and anti-inflammatory potency , can be exploited for therapeutic application in oral microbial infections.
CFN90059 Pimaricin

Pimaricin is an effective, broad spectrum antifungal, it also exhibits reduced (oral and topical) toxicity to humans, which is probably associated with the lack of effects on mammalian cell membranes.
CFN99402 Pimpinellin

Pimpinellin has phototoxic, it acts as antagonist of proteins with GABA receptor activity. Pimpinellin has anti- inflammatory, and cytotoxic activities. Pimpinellin also has anti-bacterial activity, it shows inhibitory activity against Mycobacterium tuberculosis strain H37Ra , with MICs of 812 uM and IC50s of 389 uM.
CFN98917 Pinobanksin

Pinobanksin and some of its ester derivatives from Sonoran propolis have apoptotic induction in a B-cell lymphoma cell line. Pinobanksin possesses considerable antimutagenic properties against ofloxacin-induced bleaching of E. gracilis. Pinobanksin inhibits peroxidation of low density lipoprotein and it has electron donor properties reducing alpha-tocopherol radicals.