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Natural Products
Catalog No. Information
CFN00422 Spartioidine

Reference standards.
CFN97150 Spathulenol

Spathulenol has immunomodulatory effect. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway; it presents moderate or low cytotoxicity with IC50 higher than 6uM, it is a good candidate to be used in combination chemotherapy of MDR cancer.
CFN00386 Spectabiline

Spectabiline shows tumor-inhibitory properties against one or more test tumors. Spectabiline, monocrotaline, sarracine, lasiocarpine, 7-angelylheliotridine, heliotrine and senecionine have similar antagonistic potencies against responses to both acetylcholine and histamine.
CFN98763 Sphondin

Sphondin may have anticonvulsant, anti-inflammatory, and anti-proliferative activities, it may act as a potent inhibitor of NO production under tissue-damaging inflammatory conditions, it also possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells through suppression of NF-kappaB activity. Sphondin, 8-methoxypsoralen, and khellin have delayed phototoxic effects inAedes aegypti.
CFN95194 Spinacetin

Spinacetin has anti-inflammatory effects, it weakly inhibited nitric oxide production and reduced prostaglandin E2 levels to different extents. It shows the activities in preventing inflammatory processes, which might be at least partially attributed to the abolishment of Syk-dependent activation of IgE/Ag-mediated mast cells.
CFN99600 Spinosin

Spinosin has neuroprotective, anxiolytic-like and anti-inflammatory effects, it ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, it also potentiated pentobarbital-induced sleep via the serotonergic system.
CFN70300 Spiraeoside

Spiraeoside has antioxidant, anti-inflammatory, ulcer preventive and gastroprotective activities, it inhibits mast cells activation and IgE-mediated allergic responses by suppressing phospholipase C-γ-mediated signaling. Spiraeoside shows anti-plasmin activity, which is considered to play a key role in UV-stimulated melanogenesis in human skin. Spiraeoside is a new inhibitor of the DENV-NS5 RdRp from Carpolepis laurifolia as a potential antiviral drug for dengue treatment.
CFN99208 Squalene

Squalene, a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.Squalene shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene can significantly suppress colonic aberrant crypt foci (ACF) formation and crypt multiplicity strengthens the hypothesis that squalene possesses chemopreventive activity against colon carcinogenesis.
CFN98506 Stachydrine hydrochloride

Stachydrine hydrochloride promotes the protein expression of IL-12 and IL-6, as well as the mRNA expression of T-bet and RORγt, while inhibiting the mRNA expression of GATA-3 and Foxp3; the Th1/Th2/Th17/Treg paradigm induced by Stachydrine hydrochloride contributed to the reduction in uterine bleeding in RU486-induced abortion mice.
CFN90424 Stachyose

Stachyose, as prebiotics, can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.Stachyose inhibits Caco-2 cell proliferation and induces apoptosis in a dose-dependent manner. Stachyose with an RS3 carrier has better preventative effects on colitis than Stachyose alone in mice.