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Natural Products
Catalog No. Information
CFN00352 Yamataimine

Reference standards.
CFN70388 Yamogenin

Reference standards.
CFN96416 Yangambin

Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests.
CFN92658 Yangonin

Yangonin is a novel CB₁ receptor ligand, it exhibits affinity for the human recombinant CB₁ receptor, it is also an effective inhibitor of EV-A71 infection in the low-micromolar. Yangonin could be a valuable candidate for the intervention of NF-κB-dependent pathological conditions such as inflammation.Yangonin induces autophagy and sensitizes bladder cancer cells to flavokawain A and docetaxel via inhibition of the mTOR pathway.
CFN98635 Yatein

Yatein is a lignan precursor of podophyllotoxin, a key agent in anticancer drugs. Yatein can significantly suppress HSV-1 multiplication in HeLa cells without apparent cytotoxicity.
CFN90147 Yohimbine

Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. Yohimbine may augment extinction learning without significant side effects, and as a therapeutic augmentation strategy for exposure therapy in social anxiety disorder. Yohimbine can be used as antagonistic agents against medetomidine-induced diuresis in healthy cats; it inhibits ATP-sensitive K+ channels in mouse pancreatic beta-cells.
CFN95127 Yuanhuanin

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CFN95179 Yuanhunine

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CFN95128 Yuankanin

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CFN92874 Yuexiandajisu D

Yuexiandajisu D is slightly active against ANA-1 cells with an IC50 value 2.88 x 10(-1)microM. It shows moderate cytotoxic activity against cancer cell lines on HCT-8 and Bel-7402, with IC50 values of 2.66 and 3.76 microM, respectively.