Hot Products
| Catalog No. | Information |
| CFN92017 | 6-Prenylnaringenin 6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin. It exhibits both mixed and non-competitive inhibitory characteristics against tyrosinase, tyrosinase is the rate-limiting enzyme for the production of melanin and other pigments via the oxidation of l-tyrosine. 6-Prenylnaringenin has anti-cancer potential , dose-dependent reduction of cellular proliferation of human PC-3 prostate cancer and UO.31 renal carcinoma cells upon treatment. 6-Prenylnaringenin can inhibit 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced inflammation (1μg/ear) in mice, it also exhibits inhibitory effects on skin-tumor promotion in anin vivo two-stagemouse-skin carcinogenesis test based on 7,12-dimethylbenz[a]- anthracene (DMBA) as initiator and with TPA as promoter. |
| CFN99531 | 6-Shogaol 6-Shogaol has anti-cancer, neuroprotective, anti-inflammatory effects, it can inhibit the growth of human pancreatic tumors and sensitize them to gemcitabine by suppressing of TLR4/NF-κB-mediated inflammatory pathways linked to tumorigenesis. 6-Shogaol induces apoptosis in human hepatocellular carcinoma cells in relation to caspase activation and endoplasmic reticulum (ER) stress signaling, affects the ER stress signaling by regulating unfolded protein response (UPR) sensor PERK and its downstream target eIF2α. |
| CFN95139 | 7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) Reference standards. |
| CFN95140 | 7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one 7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's disease (AD). |
| CFN96001 | 7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin Reference standards. |
| CFN97786 | 7,3',4'-Trihydroxyflavone 3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclastogenesis via nuclear factor of activated T cells c1 (NFATc1). |
| CFN92389 | 7,3'-Dihydroxy-5'-methoxyisoflavone 7,3'-Dihydroxy-5'-methoxyisoflavone shows moderate activity against the renal, melanoma and breast cancer cell lines, it may have a synergistic effect with other anticancer drugs. |
| CFN98819 | 7,4'-Di-O-methylapigenin Apigenin 7, 4'-dimethyl ether (7,4'-Di-O-methylapigenin) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines. |
| CFN94465 | 7,8-Benzoflavone 7,8-Benzoflavone is one of the most potent inhibitors of breast cancer resistance protein (BCRP). |
| CFN96512 | 7,8-Dihydroxyflavone 7,8-Dihydroxyflavone(7,8-DHF) shows vasorelaxing , antihypertensive, anti-inflammatory and anti-oxidant properties, it can be used as a potent facultative ingredient in health-beneficial agents to prevent or treat the skin aging or inflammatory skin disorders. 7,8-DHF has anti-obesity activity, it improves mitochondrial respiration in STs from obese women, it is beneficial for both depression and anxiety-like behaviors, and may exert fast-onset antidepressant effects. 7,8-DHF exhibits anti-melanogenic activity through inhibition of tyrosinase activity in α-MSH-stimulating condition, it also shows anticancer activity in melanoma cells via downregulation of α-MSH/cAMP/MITF pathway. 7,8-DHF ameliorates motor deficits via suppressing α-synuclein expression and oxidative stress in the MPTP-induced mouse model of Parkinson's disease. |
