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Natural Products
Catalog No. Information
CFN98656 Acuminatin

(-)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity against platelet aggregation with IC50 values of 108.5 and 90.02 uM, respectively.(-)-Acuminatin, and machilin G show dose-dependent potent inhibitory activities against PLCgamma1 in vitro with IC50 values ranging from 8.8 to 26.0 microM, the inhibition of PLCgamma1 may be an important mechanism for an antiproliferative effect on the human cancer cells, therefore, these inhibitors may be utilized as cancer chemotherapeutic and chemopreventive agents.
CFN99215 Adenanthin

Adenanthin is a novel NF-κB and nucleophilic cysteines inhibitor, it has bacteriostatic, antiinflammatory, and antitumour activities. Adenanthin also has antileukemic activity through targeting peroxiredoxin I/II. Adenanthin can serve as the development of Prx I– and Prx II–targeted therapeutic agents.
CFN89041 Adenine

Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. Adenine, an AMP-activated protein kinase (AMPK) activator, can accelerate the diabetic wound healing by PPAR delta and angiogenic regulation; it also can increase the inhibitory activity of human interferon against encephalomyocarditis virus. Adenine can act as an efficient radiation-protecting agent at low concentration (2 micromol) and also inhibit cytostatic properties with regard to cancer cells at higher concentration.
CFN98992 Adenosine

Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Adenosine induces SphK1 activity in human and mouse sickle and normal erythrocytes in vitro, it can activate the neuroimmune system, alter neuronal function and neurotransmission,and contribute to symptoms of sickness and psychopathologies. Adenosine activates mast cells have been long implicated in allergic asthma and studies in rodent mast cells have assigned the A3 Adenosine receptor (A3R) a primary role in mediating Adenosine responses.
CFN90031 Adenosine cyclophosphate

Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect,and it can improve cardiac function of patients and improve immune function. Combined Puerarin with meglumine adenosine cyclophosphate in treating refractory heart failure is effective and safe.
CFN00344 Adonifoline

Adonifoline is a hepatotoxic pyrrolizidine alkaloid.
CFN90032 Adrenaline

L-Epinephrine is a hormone secreted by the medulla of the adrenal glands. L-Epinephrine is an α-adrenergic and β-adrenergic receptor agonist.Epinephrine-MC RDSTs facilitated a twofold increase in epinephrine absorption and a 50% reduction in the sublingual dose, this novel sublingual tablet formulation is potentially useful for the first-aid treatment of anaphylaxis in community settings. Pre-hospital administration of Adrenaline by emergency medical services improves the long term outcome in patients with out of hospital cardiac arrest, although the absolute increase of neurologically intact survival was minimal.
CFN97751 Adynerin

Standard reference
CFN91133 Aegeline

Aegeline has anti-diabetic and anti-dyslipidemic activities, it inspired synthesis of novel amino alcohol and thiazolidinedione hybrids with antiadipogenic activity in 3T3-L1 cells, it also inspired synthesis of novel β3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance. Aegeline mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast.
CFN92621 Aerugidiol

Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B).