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Natural Products
Catalog No. Information
CFN97272 9-Oxo-10,11-dehydroageraphorone

9-Oxo-10,11-dehydroageraphorone has acaricidal activity. It induces hepatotoxicity and cholestasis in rats. 9-Oxo-10,11-dehydroageraphorone also effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M phase.
CFN70330 a,b-Elemolic acid

Reference standards.
CFN00001 AAL Toxin TA1

AAL-toxins TA 1 and TA 2 are host-specific toxins (HST) produced by Altemaria altemata f. sp. lycopersici, a causal fungus of tomato stem canker.
CFN93019 Aaptamine

Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner. Aaptamine is a competitive antagonist of alpha-adrenoceptors in vascular smooth muscles. Aaptamine has potent cytotoxicity that may be explained by its ability to intercalate DNA, it exerts an antiproliferative effect against NT2-R, a cisplatin-resistant subline of the human embryonal carcinoma cell line NT2. Aaptamine shows anti-photoaging effect in UVB-irradiated human dermal fibroblasts and epidermal keratinocytes. Aaptamine also has anti-antiviral activity.
CFN90587 Abietic acid

Abietic acid, an abietane diterpenoid, inhibited soybean 5-lipoxygenase with an IC50 of 29.5 ± 1.29 μM.Abietic acid acts as a PPARα/γ dual activator to inhibit UVB-induced MMP-1 expression and age-related inflammation by suppressing NF-κB and the MAPK/AP-1 pathway and can be a useful agent for improving skin photoageing. Abietic acid can be used not only for anti-inflammation but also for regulating lipid metabolism and atherosclerosis.
CFN90202 Abrine

Abrine shows comparable ABTS radical cation scavenging activities and reduces power to two commercial antioxidants (BHT and Trolox).
CFN90051 Abscisic acid

Abscisic acid (ABA) is a ubiquitous hormone that regulates plant growth, development and responses to environmental stresses, plays a crucial role in the plant's response to both biotic and abiotic stress. Treatment with low concentrations of abscisic acid ( 10 to 100 microM) induced an antioxidative defence response against oxidative damage, but a high concentration of ABA (1,000 microM) induced an excessive generation of AOS and led to an oxidative damage in plant cells.
CFN90168 Absinthiin

Absinthin is a natural bitter flavoring constituent.
CFN00101 Aburatubolactam A

Aburatubolactam A is an inhibitor of superoxide anion generation. It has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging.
CFN98744 Acacetin

Acacetin is an atrium-selective agent that prolongs the atrial effective refractory period without prolonging the corrected QT interval and effectively prevents atrial fibrillation (AF) in anesthetized dogs after intraduodenal administration. Acacetin has anti-cancer, anti-mutagenic, spasmolytic and antinociceptive, anti-inflammatory and anti-peroxidative effects.