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- 2. Pharmacological research
- 3. Inhibitors
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone
ChemFaces products have been cited in many studies from excellent and top scientific journals
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $268 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
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- The Institute of Cancer Research (United Kingdom)
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Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone may have antifungal activity against phytopathogenic and human pathogenic fungi. |
| Targets: |
Antifection |
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone Description
| Source: |
The fruits of Citrus aurantifolia. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.3901 mL |
11.9506 mL |
23.9011 mL |
47.8023 mL |
59.7529 mL |
| 5 mM |
0.478 mL |
2.3901 mL |
4.7802 mL |
9.5605 mL |
11.9506 mL |
| 10 mM |
0.239 mL |
1.1951 mL |
2.3901 mL |
4.7802 mL |
5.9753 mL |
| 50 mM |
0.0478 mL |
0.239 mL |
0.478 mL |
0.956 mL |
1.1951 mL |
| 100 mM |
0.0239 mL |
0.1195 mL |
0.239 mL |
0.478 mL |
0.5975 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| An Acad Bras Cienc. 2007 Jun;79(2):215-22. | | Complete H-1 and C-13 NMR assignments and antifungal activity of two 8-hydroxy flavonoids in mixture.[Pubmed: 17625676] |
METHODS AND RESULTS:
A mixture of the two new flavonols 8-hydroxy-3,4',5,6,7-pentamethoxyflavone (1) and 8-hydroxy-3,3',4' 5,6,7-hexamethoxyflavone (8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone,2) was isolated from a commercial sample of Citrus aurantifolia.
An array of one- ((HNMR)-H-1, {H-1}-C-13 NMR, and APT-C-13 NMR) and two-dimensional NMR techniques (COSY, NOESY, HMQC and HMBC) was used to achieve the structural elucidation and the complete H-1 and C-13 chemical shift assignments of these natural compounds.
CONCLUSIONS:
In addition, the antifungal activity of these compounds against phytopathogenic and human pathogenic fungi was investigated. |
|
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