Hot Products
| Catalog No. | Information |
| CFN93076 | Bacopaside I Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid. Bacopaside I also exhibits an obvious antidepressant-like effect in mouse model of CUMS-induced depression that was mediated, at least in part, by modulating HPA hyperactivity and activating BDNF signaling pathway. |
| CFN93234 | Bacopaside II Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis. Bacopaside II shows antioxidant and antidepressant activities, it can inhibit both basal activity as well as verapamil-stimulated ATPase activity, suggesting its affinity towards P-gp. |
| CFN91182 | Bacopaside IV Reference standards. |
| CFN91081 | Bacopaside N2 Reference standards. |
| CFN93267 | Bacopaside V Reference standards. |
| CFN91082 | Bacopaside X Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor. |
| CFN91080 | Bacoside A Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidative stress by an increase in the concentration of antioxidant enzymes and sustain membrane integrity which leads to restoring the damage caused by tBHP. Bacoside A can able to inhibit the progression of Experimental Autoimmune Encephalomyelitis (EAE) may be by the inhibition of inflammatory cytokines and chemokine evolved during active EAE. Bacoside A also has vasorelaxation. |
| CFN91088 | Bacoside A3 Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS. Bacoside A3 shows a newer potential role in the clinical management of opioid withdrawal induced depression. Bacoside A3 inhibited both basal activity as well as verapamil-stimulated ATPase activity, thus its affinity towards P-gp; the interaction of bacosides (A3/A) with Tryptophan hydroxylase (TPH) might up-regulate its activity to elevate the biosynthesis of 5-HT, thereby enhances learning and memory formation. |
| CFN98783 | Baicalein Baicalein has neuroprotective, anticancer, antioxidant and free radical scavenging effects, it inhibits mTORC1 pathway and PI3K kinase activity. Baicalein is mainly due to autophagic cell death through activation of the AMPK/ULK1 pathway and inhibition of mTOR/Raptor complex 1 expression; it can induce cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT. |
| CFN92361 | Baicalein 6-O-glucoside Baicalein 6-O-glucoside is a natural product from Thymus serpyllum L. |
