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Natural Products
Catalog No. Information
CFN90628 Asarinin

Asarinin, a mammalian lignan precursor, has immunosuppression activity and can inhibit acute rejection in vitro. Asarinin may have a role on TLR4 pathway and produce prolongation of allograft heart survival. Asarinin induces dopamine biosynthesis via activation of the PKA-CREB-TH system and protects against 6-OHDA-induced cytotoxicity by inhibiting the sustained activation of the ERK-p38MAPK-JNK1/2-caspase-3 system in PC12 cells.
CFN89486 Asatone

Asatone has antifeedant activity.
CFN90048 Ascorbic acid

Ascorbic acid (Vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, it has a protective effect on alloxan-induced damage by maintaining the activity of cellular antioxidants, it also protects sperm from endogenous oxidative DNA damage that could affect sperm quality and increases risk of genetic defects, particularly in populations with low ascorbic acid such as smokers.Ascorbic acid can reverse endothelial vasomotor dysfunction in the brachial circulation of patients with coronary artery disease.
CFN96928 Asebogenin

Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, respectively); it shows antiplasmodial activities against both a chloroquine-sensitive and a resistant strain of Plasmodium falciparum. Asebogenin can inhibit the proliferation of murine B cells.
CFN96929 Asebotin

Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit the proliferation of murine B cells.
CFN98688 Asiatic acid

Asiatic acid shows antihyperlipidemic, anti-inflammatory, antioxidant, and anti-tumorigenesis effects, it inhibits NLRP3 inflammasome activation, NO and COX-2 signals. Asiatic acid inhibits the expression NDR1/2 kinase and promotes the stability of p21WAF1/CIP1 protein through attenuating NDR1/2 dependent phosphorylation of p21WAF1/CIP1 in HepG2 cells.
CFN99912 Asiaticoside

Asiaticoside, a biochemical modulator, which has antioxidant, anti-inflammatory, antipyretic, anxiolytic-like, anti-gastric ulcers, hepatoprotective, and antidepressant-like effects, it also exhibits significant wound healing activity in normal as well as delayed healing models. Asiaticoside suppressed collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts. It and its derivatives can be regarded as reasonable candidates for a therapeutic Alzheimer's disease drug that protects neurons from Abeta toxicity.
CFN95124 Asiaticoside B

Asiaticoside B has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
CFN96772 Asimilobine

(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minimum inhibition concentration (MIC) of 0.25 mg/mL.
CFN98937 Asperglaucide

Asperglaucide shows some nematocidal property against M. incognita.