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Bioactive Products
Inhibitors Compound Library
A unique collection of 267 Inhibitor natural compounds
Catalog No: Bb221 Inhibitors Compound Library
Screening Details
Size: 1mg/well * 267 Compounds
2mg/well * 267 Compounds
Cat. No. Information
CFN98776 Butein

Butein is a chelator of ferrous and copper ions, is able to inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, also inhibits EGFR. Butein can inactivate PMA-activated AP-1, due to the blocking of JNK-mediated c-Jun phosphorylation through the inhibition of ATP binding. Butein has potent anticancer, anti-inflammatory, antioxidant activities, it also has a hypotensive effect, at least in part, via the inhibition of angiotensin converting enzyme.
CFN98778 vibo-Quercitol

(-)-vibo-Quercitol is a carbaglycosylamine glycosidase inhibitor.
CFN98780 Robinetin

Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. Robinetin also has anti-mutagenesis and anti-promotion effects, diminishes ornithine decarboxylase activity induction at 6 h after 12-O-tetradecanoyl phorbol-13-acetate. Robinetin leads to the occurrence of positive induced circular dichroism (ICD) bands in the near ultra-violet (UV) region.
CFN98805 Rosenonolactone

Rosenonolactone shows inhibitory activity against prolyl endopeptidase and thrombin.
CFN98590 Rotenone

Rotenone is a mitochondrial complex I inhibitor that produces an animal model of Parkinson's disease. Rotenone-induced α-synuclein aggregation is mediated by the calcium/GSK3β signaling pathway. Rotenone can increase intracellular levels of the toxic dopamine metabolite 3,4-dihydroxyphenyl-acetaldehyde (DOPAL), via decreasing DOPAL metabolism by aldehyde dehydrogenase (ALDH) and decreasing vesicular sequestration of cytoplasmic dopamine by the vesicular monoamine transporter (VMAT).