Bioactive Products
| A unique collection of 267 Inhibitor natural compounds | ||
| Catalog No: | Bb221 | Inhibitors Compound Library Screening Details |
| Size: | 1mg/well * 267 Compounds 2mg/well * 267 Compounds | |
| Cat. No. | Information |
| CFN98887 | Scopolin Scopolin exhibits significant and dose-related antinociceptive effects, it is a potential acetylcholinesterase (AChE) inhibitor. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, it may be a potent agent for angiogenesis related diseases.Scopolin and related coumarins has fungitoxic effect on Sclerotinia sclerotiorum, which is a way to overcome sunflower head rot. |
| CFN98891 | 1,3,5-Trihydroxy-4-prenylxanthone 1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 56.3plusmn;0.4 and 46.0plusmn;0.3 M, respectively. 1,3,5-Trihydroxy-4-prenylxanthone inhibits LPS-induced NF-κB and AP-1 activations by interfering with the posttranslational modification (phosphorylation and/or ubiquitinylation) of IRAK-1 in the cell membrane to impede TAK1-mediated activation of IKK and MAPKs signal transduction. |
| CFN98895 | 1-Hydroxyrutaecarpine 1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro. It exhibits antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 micrograms/ml.1-Hydroxyrutaecarpine displays moderate inhibitory activity on those enzymes(Cathepsins B, L and K) at the concentration of 125 ug/ml. |
| CFN00101 | Aburatubolactam A Aburatubolactam A is an inhibitor of superoxide anion generation. It has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging. |
| CFN00102 | Aflastatin A Aflastatin A exhibits antimicrobial activity against some bacteria, yeasts and fungi, it is a specific inhibitor of aflatoxin production by Aspergillus parasiticus, inhibits a very early step in aflatoxin biosynthesis prior to the transcription of aflR and can influence glucose metabolism in the fungus. Aflastatin A has antitumor activity. Aflastatin A inhibits an early step in melanin production, which suppresses the expression of PKS1. |
