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1-Hydroxycanthin-6-one
1-Hydroxycanthin-6-one
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1-Hydroxycanthin-6-one
Price:
CAS No.: 80787-59-3
Catalog No.: CFN97287
Molecular Formula: C14H8N2O2
Molecular Weight: 236.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Yellow powder
Source: The barks of Picrasma quassioides (D.Don) Benn
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Plant Cell Rep. 1986 Oct;5(5):387-90.
Studies on Ailanthus altissima cell suspension cultures : Precursor feeding of L-[methylene-(14)C]tryptophan and L-tryptophan.[Pubmed: 24248306]

METHODS AND RESULTS:
The uptake of L-[methylene (14)C]-tryptophan from culture medium and the subsequent incorporation of the radiolabel into canthin-6-one, 1-Hydroxycanthin-6-one and 1-methoxycanthin-6-one has been demonstrated in cell suspension cultures of Ailanthus altissima. Efficient incorporation has been shown to depend significantly on the time of feeding. Furthermore, feeding of L-tryptophan, at levels of 500 mg/l resulted in improved alkaloid yields, particularly when fed during the lag phase of the growth cycle.
1-Hydroxycanthin-6-one Description
Source: The barks of Picrasma quassioides (D.Don) Benn
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2337 mL 21.1685 mL 42.337 mL 84.674 mL 105.8425 mL
5 mM 0.8467 mL 4.2337 mL 8.4674 mL 16.9348 mL 21.1685 mL
10 mM 0.4234 mL 2.1169 mL 4.2337 mL 8.4674 mL 10.5843 mL
50 mM 0.0847 mL 0.4234 mL 0.8467 mL 1.6935 mL 2.1169 mL
100 mM 0.0423 mL 0.2117 mL 0.4234 mL 0.8467 mL 1.0584 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN98730Canthin-6-one479-43-6220.2 C14H8N2O
CFN92010Canthin-6-one N-oxide60755-87-5236.2C14H8N2O2
CFN972871-Hydroxycanthin-6-one80787-59-3236.2 C14H8N2O2
CFN921269-Hydroxycanthin-6-one138544-91-9236.2C14H8N2O2
CFN9401210-Hydroxycanthin-6-one86293-41-6236.23C14H8N2O2
CFN920119-Methoxycanthin-6-one74991-91-6250.3C15H10N2O2
CFN920129-Methoxycanthin-6-one-N-oxide137739-74-3266.3C15H10N2O3
CFN921241-Hydroxy-9-medroxycanthin-6-one622408-85-9266.3C15H10N2O3
CFN9212511-Hydroxycanthin-6-one75969-83-4236.2C14H8N2O2
CFN921279,10-Dimethoxycanthin-6-one155861-51-1280.3C16H12N2O3
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