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13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide
ChemFaces products have been cited in many studies from excellent and top scientific journals
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| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
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Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide is a natural product from Artemisia myriantha. |
13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide Description
| Source: |
The aerial parts of Artemisia myriantha. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.2642 mL |
16.3212 mL |
32.6424 mL |
65.2848 mL |
81.606 mL |
| 5 mM |
0.6528 mL |
3.2642 mL |
6.5285 mL |
13.057 mL |
16.3212 mL |
| 10 mM |
0.3264 mL |
1.6321 mL |
3.2642 mL |
6.5285 mL |
8.1606 mL |
| 50 mM |
0.0653 mL |
0.3264 mL |
0.6528 mL |
1.3057 mL |
1.6321 mL |
| 100 mM |
0.0326 mL |
0.1632 mL |
0.3264 mL |
0.6528 mL |
0.8161 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Phytochemistry. 2002 Mar;59(5):529-36. | | Germacranolides from Artemisia myriantha and their conformation.[Pubmed: 11853748] |
METHODS AND RESULTS:
The CH(2)Cl(2) extract of the aerial parts of Artemisia myriantha afforded three germacranolides derived from 13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide, whose structures were elucidated by 2D-NMR spectroscopic analyses. Some conclusions are drawn about the possible conformations of the ten-membered germacranolide ring system from the exchange peaks seen in the NOESY spectra, and an estimate is made of the energy barrier to ring-flipping from variable-temperature NOESY experiments.
CONCLUSIONS:
The conclusions reached were supported by molecular modeling studies and an NMR spectroscopic investigation of the commercially available germacranolide, parthenolide. |
|
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