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14-Deoxy-17-hydroxyandrographolide
14-Deoxy-17-hydroxyandrographolide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 14-Deoxy-17-hydroxyandrographolide
Price:
CAS No.: 869384-82-7
Catalog No.: CFN97601
Molecular Formula: C20H32O5
Molecular Weight: 352.47 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Oil
Source: The herbs of Andrographis paniculata (Burm. f.) Nees
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Standard reference
Targets: Antifection
14-Deoxy-17-hydroxyandrographolide Description
Source: The herbs of Andrographis paniculata (Burm. f.) Nees
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8371 mL 14.1856 mL 28.3712 mL 56.7424 mL 70.928 mL
5 mM 0.5674 mL 2.8371 mL 5.6742 mL 11.3485 mL 14.1856 mL
10 mM 0.2837 mL 1.4186 mL 2.8371 mL 5.6742 mL 7.0928 mL
50 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.1348 mL 1.4186 mL
100 mM 0.0284 mL 0.1419 mL 0.2837 mL 0.5674 mL 0.7093 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 2006 Mar;69(3):319-22.
ent-Labdane diterpenoids from Andrographis paniculata.[Pubmed: 16562826]

METHODS AND RESULTS:
Six new ent-labdane diterpenoids, 3-O-beta-D-glucopyranosyl-14,19-dideoxyandrographolide (1), 14-Deoxy-17-hydroxyandrographolide (2), 19-O-[beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoyl]-3,14-dideoxyandrographolide (3), 3-O-beta-d-glucopyranosylandrographolide (4), 12S-hydroxyandrographolide (5), and andrographatoside (6), together with 17 known analogues, were isolated from the aerial parts of Andrographis paniculata. The structures of 1-6 were determined by spectroscopic data analysis. All compounds isolated were evaluated for their inhibitory activity against several bacterial and fungal strains.
CFN9781514-Deoxy-11-hydroxyandrographolide160242-09-1350.45C20H30O5
CFN9778514-Deoxy-12-hydroxyandrographolide219721-33-2350.45C20H30O5
CFN96446Vitexolide D1788090-69-6318.45C20H30O3
CFN91445Isoandrographolide4176-96-9350.5C20H30O5
CFN98923Andrographolide5508-58-7350.5 C20H30O5
CFN9866614-Deoxy-11,12-didehydroandrographolide42895-58-9332.4 C20H28O4
CFN99770Dehydroandrographolide134418-28-3332.43C20H28O4
CFN9280214-Deoxyandrographolide4176-97-0334.45C20H30O4
CFN90518Deoxyandrographolide79233-15-1334.45C20H30O4
CFN9760114-Deoxy-17-hydroxyandrographolide869384-82-7352.47C20H32O5
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