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1beta-Hydroxytorilin
1beta-Hydroxytorilin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1beta-Hydroxytorilin
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CAS No.: 509078-16-4
Catalog No.: CFN96793
Molecular Formula: C22H32O6
Molecular Weight: 392.49 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Oil
Source: The fruits of Torilis japonica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 1beta-Hydroxytorilin exhibits cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.
In vitro:
Arch Pharm Res. 2006 Feb;29(2):131-4.
Guaiane sesquiterpenoids from Torilis japonica and their cytotoxic effects on human cancer cell lines.[Pubmed: 16526276]

METHODS AND RESULTS:
A new compound 2 and two known guaiane-type sesquiterpenoids were isolated from the methylene chloride-soluble fraction of the methanolic extract of the fruits of Torilis japonica (Umbelliferae) through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as torilin (1), 11-acetoxy-8-angeloyloxy-1beta-hydroxy-4-guaien-3-one (1beta-Hydroxytorilin, 2), and 11-acetoxy-8-angeloyloxy-1alpha-hydroxy-4-guaien-3-one (1alpha-hydroxytorilin, 3) by spectroscopic analysis.
CONCLUSIONS:
Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.
1beta-Hydroxytorilin Description
Source: The fruits of Torilis japonica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5478 mL 12.7392 mL 25.4784 mL 50.9567 mL 63.6959 mL
5 mM 0.5096 mL 2.5478 mL 5.0957 mL 10.1913 mL 12.7392 mL
10 mM 0.2548 mL 1.2739 mL 2.5478 mL 5.0957 mL 6.3696 mL
50 mM 0.051 mL 0.2548 mL 0.5096 mL 1.0191 mL 1.2739 mL
100 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.5096 mL 0.637 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN99634Teuclatriol152110-17-3256.4 C15H28O3
CFN98560Atractyloside A126054-77-1448.5C21H36O10
CFN89350Isonardoperoxide205248-65-3266.33C15H22O4
CFN92654Orobanone78916-35-5216.3C15H20O
CFN92652Zedoarondiol98644-24-7252.4C15H24O3
CFN95848Isozedoarondiol108887-68-9252.4C15H24O3
CFN92620Isoprocurcumenol102130-90-5234.3C15H22O2
CFN92647Procurcumenol21698-40-8234.3C15H22O2
CFN91614Epiprocurcumenol127214-97-5234.33C15H22O2
CFN92621Aerugidiol116425-35-5250.3C15H22O3
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