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2,3-O-Isopropylidenyl euscaphic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2,3-O-Isopropylidenyl euscaphic acid
Price:
CAS No.: 220880-90-0
Catalog No.: CFN98095
Molecular Formula: C33H52O5
Molecular Weight: 528.8 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The dried fruit of Ziziphus jujuba.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 2,3-O-Isopropylidenyl euscaphic acid shows good hepatoprotective effect,the EC50 value of 88.36±3.25 uM in Hep G2 cells.
2,3-O-Isopropylidenyl euscaphic acid Description
Source: The dried fruit of Ziziphus jujuba.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8911 mL 9.4554 mL 18.9107 mL 37.8215 mL 47.2769 mL
5 mM 0.3782 mL 1.8911 mL 3.7821 mL 7.5643 mL 9.4554 mL
10 mM 0.1891 mL 0.9455 mL 1.8911 mL 3.7821 mL 4.7277 mL
50 mM 0.0378 mL 0.1891 mL 0.3782 mL 0.7564 mL 0.9455 mL
100 mM 0.0189 mL 0.0946 mL 0.1891 mL 0.3782 mL 0.4728 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Traditional & Herbal Drugs, 2003, 32(16):1663-5.
Chemical constituents from root of Rubus irenaeus.[Reference: WebLink]
To investigate the chemical constituents from the methanol extract of the root of Rubus irenaeus Focke.
METHODS AND RESULTS:
EtOAc extraction, normal and reverse phase silica gel column chromatography were used for isolation. Spectroscopic methods ( 13 CNMR , 1HNMR , DEPT, 2DNMR, and FAB-MS) and comparison with authentic samples were used for identification. Ten compounds were isoated and characterized as 2α, 19α-dihydroxyl-3-oxo-urs-12-en-28-oic acid (Ⅰ), 2-oxo-pomolic acid (Ⅱ), fupenzic acid (Ⅲ), euscaphic acid (Ⅳ), 2α, 3α, 19α-trihydroxyl-olean-12-en-28-oic acid (Ⅴ),2,3-O-Isopropylidenyl euscaphic acid (Ⅵ), pomolic acid (Ⅶ), 2α, 3β-dihydroxyl-lup-20(29)-en-28-oic acid(Ⅷ), catechin (Ⅸ) and daucosterol (Ⅹ).
CONCLUSIONS:
These compounds were obtained from this plant for the first time.
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