2',4'-Dihydroxy-7-methoxy-8-prenylflavan | CAS:331954-16-6

2',4'-Dihydroxy-7-methoxy-8-prenylflavan

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Description:

Reference standards.

In vitro:

Fitoterapia, 2014, 98:222-227.

Chemical constituents of Morus alba L. and their inhibitory effect on 3T3-L1 preadipocyte proliferation and differentiation.[Reference: WebLink]

Mulberry leaf, an important traditional Chinese medicine, possesses many biological activities, including effects of anti-obesity. However, which constituents of mulberry leaf are responsible for its anti-adipogenic action is unclear.
METHODS AND RESULTS:
This study primarily investigated the chemical constituents from mulberry leaf and their bioactivity on the proliferation and differentiation of 3T3-L1 preadipocytes. A new flavane derivative, (2S)-4′-hydroxy-7-methoxy-8-prenylflavan (2',4'-Dihydroxy-7-methoxy-8-prenylflavan,1), together with twelve known compounds including three flavanes (2–4), three chalcones (5–7), two flavones (8–9), two benzofurans (10–11) and two coumarin (12–13) was isolated from mulberry leaf. The structure of the new compound was elucidated by various spectroscopic methods including UV, HR-ESI-MS, 1H and 13C NMR and CD.
CONCLUSIONS:
The results of activity screening showed that compound 2, 6 and 7 inhibited the proliferation and differentiation of 3T3-L1 preadipocytes.

2',4'-Dihydroxy-7-methoxy-8-prenylflavan Description

Source:	The leaves of Mulberry.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	2',4'-Dihydroxy-7-methoxy-8-prenylflavan
Price:
CAS No.:	331954-16-6
Catalog No.:	CFN96531
Molecular Formula:	C₂₁H₂₄O₄
Molecular Weight:	340.42 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The leaves of Mulberry.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.9375 mL	14.6877 mL	29.3755 mL	58.751 mL	73.4387 mL
5 mM	0.5875 mL	2.9375 mL	5.8751 mL	11.7502 mL	14.6877 mL
10 mM	0.2938 mL	1.4688 mL	2.9375 mL	5.8751 mL	7.3439 mL
50 mM	0.0588 mL	0.2938 mL	0.5875 mL	1.175 mL	1.4688 mL
100 mM	0.0294 mL	0.1469 mL	0.2938 mL	0.5875 mL	0.7344 mL

CFN96480	Trilepisflavan	1443218-16-3	286.32	C₁₇H₁₈O₄
CFN99264	3',4',7-Trimethoxyflavan	116384-26-0	300.4	C₁₈H₂₀O₄
CFN96528	7,4'-Dihydroxy-8-methylflavan	82925-55-1	256.30	C₁₆H₁₆O₃
CFN92674	2H-1-Benzopyran-5-ol	770729-34-5	286.3	C₁₇H₁₈O₄
CFN96531	2',4'-Dihydroxy-7-methoxy-8-prenylflavan	331954-16-6	340.42	C₂₁H₂₄O₄
CFN98606	7,4'-Dihydroxy-3'-prenylflavan	376361-96-5	310.4	C₂₀H₂₂O₃
CFN97839	Kazinol U	1238116-48-7	326.39	C₂₀H₂₂O₄
CFN92431	Kazinol A	99624-28-9	394.5	C₂₅H₃₀O₄
CFN97569	Kazinol B	99624-27-8	392.5	C₂₅H₂₈O₄
CFN97811	7,3'-Dihydroxy-4'-methoxyflavan	162290-05-3	272.30	C₁₆H₁₆O₄