20-O-Acetylingenol-3-angelate | CAS:82425-35-2

20-O-Acetylingenol-3-angelate

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20-O-Acetylingenol-3-angelate Description

Source:	The seeds of Euphorbia lathyris L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

US 20140350120 A1[P]. 2014.

Topical composition comprising an ingenol derivative and a surfactant-cosolvent mixture.[Reference: WebLink]

METHODS AND RESULTS:
The term “ingenol derivative” is intended to mean an ingenol compound isolated from a species of Euphorbia, in particular from E. peplus, or an ingenol derivative prepared by chemical synthesis or by a semi-synthetic route, e.g. as disclosed in copending application No. PCT/DK2011/000081. Examples of ingenol derivatives that may be included in the present compositions are ingenol-3-angelate, ingenol-5-angelate, ingenol-20-angelate, 20-O-Acetylingenol-3-angelate and 20-deoxy-ingenol-3-angelate.
CONCLUSIONS:
Ingenol-3-angelate, also known as ingenol-3-mebutate or PEP 005, is currently in development for the treatment of actinic keratosis.

Product Name	20-O-Acetylingenol-3-angelate
Price:
CAS No.:	82425-35-2
Catalog No.:	CFN93023
Molecular Formula:	C₂₇H₃₆O₇
Molecular Weight:	472.57 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The seeds of Euphorbia lathyris L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1161 mL	10.5804 mL	21.1609 mL	42.3218 mL	52.9022 mL
5 mM	0.4232 mL	2.1161 mL	4.2322 mL	8.4644 mL	10.5804 mL
10 mM	0.2116 mL	1.058 mL	2.1161 mL	4.2322 mL	5.2902 mL
50 mM	0.0423 mL	0.2116 mL	0.4232 mL	0.8464 mL	1.058 mL
100 mM	0.0212 mL	0.1058 mL	0.2116 mL	0.4232 mL	0.529 mL

CFN92861	Kansuiphorin C	133898-77-8	478.6	C₂₉H₃₄O₆
CFN92823	Phorbol	17673-25-5	364.4	C₂₀H₂₈O₆
CFN95773	Prostratin	60857-08-1	390.5	C₂₂H₃₀O₆
CFN96927	Phorbol 13-acetate	32752-29-7	406.47	C₂₂H₃₀O₇
CFN90368	12-O-Tiglylphorbol-13-isobutyrate	92214-54-5	516.62	C₂₉H₄₀O₈
CFN95825	Fischeroside A	1307257-07-3	552.6	C₂₈H₄₀O₁₁
CFN95826	Fischeroside B	1307257-08-4	704.7	C₃₅H₄₄O₁₅
CFN95824	Euphopiloside A	1610615-04-7	510.6	C₂₆H₃₈O₁₀
CFN90923	Ingenol-5,20-acetonide	77573-43-4	388.5	C₂₃H₃₂O₅
CFN93015	Ingenol-5,20-acetonide-3-O-angelate	87980-68-5	470.60	C₂₈H₃₈O₆