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(2RS)-Lotaustralin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name (2RS)-Lotaustralin
Price: $268 / 5mg
CAS No.: 1973415-50-7
Catalog No.: CFN90968
Molecular Formula: C11H19NO6
Molecular Weight: 261.27 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Rhodiola rosea L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $152.6 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: (2RS)-Lotaustralin is a natural product from Rhodiola rosea L.
In vitro:
Toxicological & Environmental Chemistry Reviews, 2016, 98(7):727-735.
Optimization of process parameters of extraction of lotaustralin from the roots of Rhodiola rosea L using supercritical CO2 plus modifier.[Reference: WebLink]
Lotaustralin((2RS)-Lotaustralin) from the root of Rhodiola rosea L was extracted using supercritical carbon dioxide with methanol as modifier.
METHODS AND RESULTS:
Response surface methodology using Box–Behnken experimental design was utilized to explore parameters for supercritical carbon dioxide extraction. The effects of various values of temperatures (50–70 °C), pressures (200--400 bar), and percentages of methanol modifier (80%–100%) on the extraction yields of lotaustralin were evaluated. Extract identification was performed using high-performance liquid chromatography. The experimental data obtained were fitted to second-order polynomial equations and assessed using analysis of variance.
CONCLUSIONS:
The highest yields predicted from the experiments were 2.05 g kg−1 lotaustralin at the optimal values, i.e. temperature 65 °C, pressure 316 bar, 88% methanol modifier at a flow rate of 0.4 mL min−1, and dynamic extraction time 90 min.
(2RS)-Lotaustralin Description
Source: The roots of Rhodiola rosea L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8275 mL 19.1373 mL 38.2746 mL 76.5492 mL 95.6865 mL
5 mM 0.7655 mL 3.8275 mL 7.6549 mL 15.3098 mL 19.1373 mL
10 mM 0.3827 mL 1.9137 mL 3.8275 mL 7.6549 mL 9.5686 mL
50 mM 0.0765 mL 0.3827 mL 0.7655 mL 1.531 mL 1.9137 mL
100 mM 0.0383 mL 0.1914 mL 0.3827 mL 0.7655 mL 0.9569 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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