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5-Acetyltaxachitriene A
5-Acetyltaxachitriene A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 5-Acetyltaxachitriene A
Price:
CAS No.: 187988-48-3
Catalog No.: CFN89119
Molecular Formula: C34H46O14
Molecular Weight: 678.72 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The needles of Taxus mairei.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: 5-Acetyltaxachitriene A is a natural product from Taxus mairei.
5-Acetyltaxachitriene A Description
Source: The needles of Taxus mairei.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4734 mL 7.3668 mL 14.7336 mL 29.4672 mL 36.834 mL
5 mM 0.2947 mL 1.4734 mL 2.9467 mL 5.8934 mL 7.3668 mL
10 mM 0.1473 mL 0.7367 mL 1.4734 mL 2.9467 mL 3.6834 mL
50 mM 0.0295 mL 0.1473 mL 0.2947 mL 0.5893 mL 0.7367 mL
100 mM 0.0147 mL 0.0737 mL 0.1473 mL 0.2947 mL 0.3683 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Natural Product Letters, 1999, 13(2):81-88.
Bicyclic Taxane With A Verticillene Skeleton From the Needles of Chinese Yew, Taxus Mairei.[Reference: WebLink]

METHODS AND RESULTS:
Two bicyclic taxanes were isolated from the needles of the Taxus mairei. One was a new compound, the structure of which was established as (3E, 7 E)-2α,5α,10β,13α,20-pentaacetox-3,8-sectoaxa-3, 7, 11-trien-9-one (1) on the basis of 1D and 2D NMR data.
CONCLUSIONS:
This is the first example of bicyclic taxane with a verticillene skeleton as a natural product. Another new natural product was identified as 5-Acetyltaxachitriene A (2).
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