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6-Hydroxyflavanone
6-Hydroxyflavanone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 6-Hydroxyflavanone
Price: $30 / 20mg
CAS No.: 4250-77-5
Catalog No.: CFN70107
Molecular Formula: C15H12O3
Molecular Weight: 240.2 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $8.9 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 6-Methoxyflavanone shows significant immunomodulatory potential.
In vivo:
Phytomedicine International Journal of Phytotherapy & Phytopharmacology, 1996, 3(2):191-5.
Actions of some flavonoids on specific and non-specific immune mechanisms.[Pubmed: 23194969]
The immunomodulatory activity of some flavonoids on antigen specific humoral and cell mediated immune responses and complement-mediated hemolysis has been investigated and compared with that of levamisole.
METHODS AND RESULTS:
Flavanone, 6-methoxyflavanone, 7-methoxyflavanone and bavachinin enhanced the sheep erythrocyte (SRBC), induced primary and secondary humoral immune responses in mice, and 6-Hydroxyflavanone, 7-hydroxyflavanone and rutin inhibited primary response. Levamisole slighly stimulated the primary and suppressed the secondary response. All the flavonoids tested decreased the manifestation of SRBC induced delayed type hypersensitivity reaction and showed no effect on classical or alternative pathway dependent hemolysis.
CONCLUSIONS:
The studies revealed the significant immunomodulatory potential of these flavonoids, methoxy derivatives having immunostimulatory activity and hydroxy derivatives immunosuppressive properties.
6-Hydroxyflavanone Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1632 mL 20.816 mL 41.632 mL 83.2639 mL 104.0799 mL
5 mM 0.8326 mL 4.1632 mL 8.3264 mL 16.6528 mL 20.816 mL
10 mM 0.4163 mL 2.0816 mL 4.1632 mL 8.3264 mL 10.408 mL
50 mM 0.0833 mL 0.4163 mL 0.8326 mL 1.6653 mL 2.0816 mL
100 mM 0.0416 mL 0.2082 mL 0.4163 mL 0.8326 mL 1.0408 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Oxymatrine

Catalog No: CFN99805
CAS No: 16837-52-8
Price: $40/20mg
Silydianin

Catalog No: CFN90242
CAS No: 29782-68-1
Price: $168/20mg
Cyanidin-3-O-rutinoside chloride

Catalog No: CFN92135
CAS No: 18719-76-1
Price: $298/10mg
Pulegone

Catalog No: CFN93286
CAS No: 89-82-7
Price: $30/20mg
Matrine

Catalog No: CFN98835
CAS No: 519-02-8
Price: $30/20mg
Rhein

Catalog No: CFN99157
CAS No: 478-43-3
Price: $40/20mg
Lasiocarpine

Catalog No: CFN00289
CAS No: 303-34-4
Price: $ /
Physalin A

Catalog No: CFN92940
CAS No: 23027-91-0
Price: $318/5 mg
Asperosaponin VI

Catalog No: CFN99766
CAS No: 39524-08-8
Price: $30/20mg
11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg
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