Structure Identification: |
Drugs & Clinic ,2014, 29 (5) :459-464. | Chemical constituents of Dipsaci Radix.[Reference: WebLink] | To study the chemical constituents of Dipsaci Radix. Methods The compounds were isolated by macroporous resin, reverse phase C18 silica gel, and semi-prepative HPLC. Their structures were identified on the basis of physicochemical properties and spectroscopic data. Results Thirteen compounds were separated, seven of which were iridoid glycosides, and six of which were lignans, identified as loganin(1), sweroside(2),
6'-O-beta-D-Apiofuranosylsweroside(3), dipsanoside H(4), dipsanoside F(5), dipsanoside E(6), triplostoside A(7),(7R, 8S, 7'R, 8'S)-5-methoxyprinsepiol-4-O-β-D-glucopyranoside(8),(7R, 8S, 7'R, 8'S)-prinsepiol-4-O-β-D-glucopyranoside(9), acanthoside D(10),(7R, 8S, 7'R, 8'S)-fraxiresinol-4'-O-β-D-glucopyranoside(11),(7R, 8S, 7'R, 8'S)-8-hydroxypinoresinol-4'-O-β-D-glucopyranoside(12), and(7R, 8S, 7'R, 8'S)-8-hydroxypinoresinol-4-O-β-Dglucopyranoside(13), respectively. Conclusion Compounds 8, 9, and 11—13 are isolated from this genus for the first time. |
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