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7-Methoxyflavone
7-Methoxyflavone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 7-Methoxyflavone
Price: $30 / 20mg
CAS No.: 22395-22-8
Catalog No.: CFN70084
Molecular Formula: C16H12O3
Molecular Weight: 252.2 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Zornia brasiliensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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Biological Activity
Description: 7-Methoxyflavone has peripheral antinociceptive activity.
7-Methoxyflavone Description
Source: The herbs of Zornia brasiliensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.9651 mL 19.8255 mL 39.6511 mL 79.3021 mL 99.1277 mL
5 mM 0.793 mL 3.9651 mL 7.9302 mL 15.8604 mL 19.8255 mL
10 mM 0.3965 mL 1.9826 mL 3.9651 mL 7.9302 mL 9.9128 mL
50 mM 0.0793 mL 0.3965 mL 0.793 mL 1.586 mL 1.9826 mL
100 mM 0.0397 mL 0.1983 mL 0.3965 mL 0.793 mL 0.9913 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Animal Research:
Natural Product Letters, 2013, 27(18):1695-1699.
Antinociceptive effect of 7-methoxyflavone isolated from Zornia brasiliensis.[Reference: WebLink]

METHODS AND RESULTS:
In this study, we investigated the antinociceptive effect of 7-Methoxyflavone (7MF) in mice using the following tests: acetic acid-induced writhing, glutamate- and formalin-induced nociception and hotplate. 7MF (30, 50, 100 and 300 μmol/kg, i.p.) reduced the number of writhes, with ID50 = 82.5 ± 11.7 μmol/kg and E max = 58.4%. 7MF treatment (100 μmol/kg, i.p.) inhibited paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase. In addition, in glutamate-induced nociception, 7MF inhibited 26% of the nociceptive answer. On the other hand, 7MF did not increase the latency time of the animals in the hotplate test.
CONCLUSIONS:
These results suggest that 7MF has peripheral antinociceptive activity.
Seneciphylline

Catalog No: CFN98747
CAS No: 480-81-9
Price: $238/5mg
Ganoderic acid F

Catalog No: CFN92055
CAS No: 98665-15-7
Price: $318/20mg
Tracheloside

Catalog No: CFN90597
CAS No: 33464-71-0
Price: $50/20mg
Cyanidin Chloride

Catalog No: CFN99741
CAS No: 528-58-5
Price: $198/20mg
Syringic acid

Catalog No: CFN98884
CAS No: 530-57-4
Price: $30/20mg
Silybin B

Catalog No: CFN92916
CAS No: 142797-34-0
Price: $368/20mg
Madecassic acid

Catalog No: CFN99914
CAS No: 18449-41-7
Price: $30/20mg
Trans-Ferulic acid

Catalog No: CFN92394
CAS No: 537-98-4
Price: $30/20mg
Hirsutenone

Catalog No: CFN98646
CAS No: 41137-87-5
Price: $ /
Astragaloside I

Catalog No: CFN99172
CAS No: 84680-75-1
Price: $50/20mg
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