Ganoderic acid F | CAS:98665-15-7 | Manufacturer ChemFaces

Ganoderic acid F

ChemFaces products have been cited in many studies from excellent and top scientific journals

Product Name	Ganoderic acid F
Price:	$318 / 20mg
CAS No.:	98665-15-7
Catalog No.:	CFN92055
Molecular Formula:	C₃₂H₄₂O₉
Molecular Weight:	570.7 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The fruiting bodys of Ganoderma lucidum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $148.8 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.

Targets:

HBV | Immunology & Inflammation related

In vivo:

Evid Based Complement Alternat Med. 2012;2012:780892.

Pharmacokinetics of ganoderic acids a and f after oral administration of ling zhi preparation in healthy male volunteers.[Pubmed: 22577465]

The objectives of this paper were to evaluate the pharmacokinetics of ganoderic acid A and Ganoderic acid F after a single oral dose of the water extract of MG2-strain Ling Zhi (MG2FB-WE) and to assess the influence of food on the pharmacokinetics in 12 healthy male volunteers.
METHODS AND RESULTS:
This study was a single-dose, open-label, randomized, two-phase crossover study with at least 2 wk washout period. Each subject was randomly assigned to receive a single oral dose of 3,000 mg of MG2FB-WE in granular formulation dissolved in 200 mL of warm water, either under a fasting condition, or immediately after a standard breakfast (fed condition). Blood samples were collected immediately before and at specific time points until 8 h after MG2FB-WE administration. Plasma ganoderic acid A and Ganoderic acid F concentrations were determined by using liquid chromatography-mass spectrometry (LC-MS) technique.
CONCLUSIONS:
In conclusion, the pharmacokinetic profile of both ganoderic acids under a fasting condition was characterized by rapid absorption from the gastrointestinal tract (T(max) at approximately 30 min) and a short elimination half-life (<40 min). Food significantly decreased C(max) and delayed T(max), but did not affect the extent of ganoderic acid A absorption. However, concomitant food intake markedly impeded both rate and extent of Ganoderic acid F absorption.

Ganoderic acid F Description

Source:	The fruiting bodys of Ganoderma lucidum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Neuroprotection Compound Library Hepatoprotective Compound Library Antiviral Compound Library Antihypertensive Compound Library Triterpenoids Compound Library Immunology & Inflammation related Inhibitor Library HBV Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7522 mL	8.7612 mL	17.5223 mL	35.0447 mL	43.8059 mL
5 mM	0.3504 mL	1.7522 mL	3.5045 mL	7.0089 mL	8.7612 mL
10 mM	0.1752 mL	0.8761 mL	1.7522 mL	3.5045 mL	4.3806 mL
50 mM	0.035 mL	0.1752 mL	0.3504 mL	0.7009 mL	0.8761 mL
100 mM	0.0175 mL	0.0876 mL	0.1752 mL	0.3504 mL	0.4381 mL

CFN95505	12beta-Acetoxy-3,7,11,15,23-pentaoxo-lanost-8,20-dien-26-oic acid	1309931-91-6	568.7	C₃₂H₄₀O₉
CFN90746	Deacetyl ganoderic acid F	100665-44-9	528.6	C₃₀H₄₀O₈
CFN92055	Ganoderic acid F	98665-15-7	570.7	C₃₂H₄₂O₉
CFN95584	Methyl ganoderate F	98665-08-8	584.7	C₃₃H₄₄O₉
CFN95515	12beta-Acetoxy-7beta-hydroxy-3,11,15,23-tetraoxo-5alpha-lanosta-8,20-dien-26-oic acid	N/A	570.7	C₃₂H₄₂O₉
CFN95469	Ganoderenic acid K	942950-94-9	572.7	C₃₂H₄₄O₉
CFN92290	Ganoderic acid C6	105742-76-5	530.7	C₃₀H₄₂O₈
CFN92292	Methyl ganoderate C6	105742-81-2	544.7	C₃₁H₄₄O₈
CFN92056	Ganoderic acid H	98665-19-1	572.7	C₃₂H₄₄O₉
CFN92291	Methyl ganoderate H	98665-11-3	586.7	C₃₃H₄₆O₉