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9-O-Methyl-4-hydroxyboeravinone B
9-O-Methyl-4-hydroxyboeravinone B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 9-O-Methyl-4-hydroxyboeravinone B
Price:
CAS No.: 333798-10-0
Catalog No.: CFN96165
Molecular Formula: C18H14O7
Molecular Weight: 342.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Mirabilis jalapa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 9-O-Methyl-4-hydroxyboeravinone B is a promising candidate for cancer therapy.
In vitro:
J Ethnopharmacol. 2014 Aug 8;155(1):326-33.
Mirabijalone E: a novel rotenoid from Mirabilis himalaica inhibited A549 cell growth in vitro and in vivo.[Pubmed: 24882730]
One new rotenoid compound, mirabijalone E, together with eight known rotenoids was isolated from Mirabilis himalaica.
METHODS AND RESULTS:
Mirabijalone E, 9-O-methyl-inone B, boeravinone C and boeravinone H exhibited cytotoxicity against A 549 and HeLa cells. Further study on mirabijalone E was carried out in vitro and in vivo. Mirabijalone E inhibited A549 cells growth in a time and dose-dependent manner, which arrested cell cycle in S phase. Mechanistically, mirabijalone E treatment resulted in the increase of Bax expression level, the decrease of Bcl-2 level and the activation of caspase-3, which suggested the activation of apoptosis cascades. Consequently, the xenograft treated with mirabijalone E showed markedly suppressed tumor growth.
CONCLUSIONS:
The result suggested that mirabijalone E, together with active compounds, 9-O-Methyl-4-hydroxyboeravinone B, boeravinone C and boeravinone H could be a promising candidate for cancer therapy.
9-O-Methyl-4-hydroxyboeravinone B Description
Source: The herbs of Mirabilis jalapa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9214 mL 14.6071 mL 29.2141 mL 58.4283 mL 73.0353 mL
5 mM 0.5843 mL 2.9214 mL 5.8428 mL 11.6857 mL 14.6071 mL
10 mM 0.2921 mL 1.4607 mL 2.9214 mL 5.8428 mL 7.3035 mL
50 mM 0.0584 mL 0.2921 mL 0.5843 mL 1.1686 mL 1.4607 mL
100 mM 0.0292 mL 0.1461 mL 0.2921 mL 0.5843 mL 0.7304 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN97864Tephrosin76-80-2410.43C23H22O7
CFN9799611-Hydroxytephrosin72458-85-6426.4C23H22O8
CFN96085Dehydrotoxicarol59086-93-0408.4C23H20O7
CFN90585Dihydrorotenone6659-45-6396.43C23H24O6
CFN98590Rotenone83-79-4394.42C23H22O6
CFN9163312-alpha-Hydroxyrotenone509-96-6410.4C23H22O7
CFN91624Amorphigenin4208-09-7410.42C23H22O7
CFN9793312-Deoxo-12alpha-acetoxyelliptone150226-21-4396.4C22H20O7
CFN97939Lupinol C135905-53-2370.4C20H18O7
CFN96204Coccineone B135626-13-0298.3C16H10O6
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