Science | Nature | Cell | View More
Natural Products
Abiesadine I
Abiesadine I
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Abiesadine I
Price:
CAS No.: 1210347-50-4
Catalog No.: CFN99330
Molecular Formula: C24H34O5
Molecular Weight: 402.5 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Pinus yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Siksha O Anusandhan University (India)
  • University of Queensland (Australia)
  • Monash University (Australia)
  • Korea Institute of Oriental Med... (Korea)
  • Biotech R&D Institute (USA)
  • Chinese University of Hong Kong (China)
  • Instituto de Investigaciones Ag... (Chile)
  • Kyoto University (Japan)
  • Universidade da Beira Interior (Germany)
  • Kyushu University (Japan)
  • Almansora University (Egypt)
  • More...
Package
Featured Products
Conduritol A

Catalog No: CFN98868
CAS No: 526-87-4
Price: $258/10mg
Pinobanksin

Catalog No: CFN98917
CAS No: 548-82-3
Price: $338/5mg
Syringaresinol-di-O-glucoside

Catalog No: CFN90458
CAS No: 66791-77-3
Price: $138/20mg
Benzoylmesaconine

Catalog No: CFN98575
CAS No: 63238-67-5
Price: $168/20mg
1,1,1-Kestopentaose

Catalog No: CFN93044
CAS No: 59432-60-9
Price: $100/20mg
Caffeic acid

Catalog No: CFN99190
CAS No: 331-39-5
Price: $30/20mg
Isoimperatorin

Catalog No: CFN99107
CAS No: 482-45-1
Price: $40/20mg
Betulin

Catalog No: CFN98710
CAS No: 473-98-3
Price: $30/20mg
Verbasoside

Catalog No: CFN95015
CAS No: 61548-34-3
Price: $318/5mg
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Bioorganic & medicinal chemistry, 2010, 18(2):744-754.
Isolation, structure, and bioactivities of abiesadines A–Y, 25 new diterpenes from Abies georgei Orr[Reference: WebLink]

METHODS AND RESULTS:
Twenty-five new (abiesadines A–Y, Abiesadine I, 1–25, ) and 29 known (26–54) diterpenes were isolated from the aerial parts of Abies georgei. Abiesadine A (1) is a novel 8,14-seco-abietane, while abiesadine B (2) is a novel 9,10-seco-abietane. The structures of the new compounds were established on the basis of spectroscopic data analysis. Manool (52) showed the strongest effect against LPS-induced NO production in RAW264.7 macrophages with the IC50 value of 11.0 μg/mL. In another anti-inflammatory assay against TNFα-triggered NF-κB activity, (12R,13R)-8,12-epoxy-14-labden-13-ol (54) exhibited the strongest effect (IC50 = 8.7 μg/mL).
CONCLUSIONS:
For antitumor assays, pomiferin A (26) and 8,11,13-abietatriene-7α,18-diol (29) both showed the most significant activity against LOVO cells (IC50 = 9.2 μg/mL). While 7-oxocallitrisic acid (46) exhibited significant cytotoxicity against QGY-7703 tumor cells (IC50 = 10.2 μg/mL).
Abiesadine I Description
Source: The herbs of Pinus yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
New compound 10

Catalog No: CFN95343
CAS No: N/A
Price: $318/5mg
Naringin 6''-acetate

Catalog No: CFN95418
CAS No: 139934-60-4
Price: $318/5mg
Tembetarine

Catalog No: CFN95542
CAS No: 18446-73-6
Price: $318/5mg
Schisphenlignan I

Catalog No: CFN95586
CAS No: 1542234-14-9
Price: $318/5mg
Silychristin B

Catalog No: CFN95160
CAS No: 879325-58-3
Price: $318/5mg
Melitidin

Catalog No: CFN95419
CAS No: 1162664-58-5
Price: $318/10mg
Glaucoside A

Catalog No: CFN95299
CAS No: 81474-91-1
Price: $318/5mg
Eriodictyol 7-O-glucuronide

Catalog No: CFN95290
CAS No: 125535-06-0
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4845 mL 12.4224 mL 24.8447 mL 49.6894 mL 62.1118 mL
5 mM 0.4969 mL 2.4845 mL 4.9689 mL 9.9379 mL 12.4224 mL
10 mM 0.2484 mL 1.2422 mL 2.4845 mL 4.9689 mL 6.2112 mL
50 mM 0.0497 mL 0.2484 mL 0.4969 mL 0.9938 mL 1.2422 mL
100 mM 0.0248 mL 0.1242 mL 0.2484 mL 0.4969 mL 0.6211 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Conduritol A

Catalog No: CFN98868
CAS No: 526-87-4
Price: $258/10mg
Pinobanksin

Catalog No: CFN98917
CAS No: 548-82-3
Price: $338/5mg
Syringaresinol-di-O-glucoside

Catalog No: CFN90458
CAS No: 66791-77-3
Price: $138/20mg
Benzoylmesaconine

Catalog No: CFN98575
CAS No: 63238-67-5
Price: $168/20mg
1,1,1-Kestopentaose

Catalog No: CFN93044
CAS No: 59432-60-9
Price: $100/20mg
Caffeic acid

Catalog No: CFN99190
CAS No: 331-39-5
Price: $30/20mg
Isoimperatorin

Catalog No: CFN99107
CAS No: 482-45-1
Price: $40/20mg
Betulin

Catalog No: CFN98710
CAS No: 473-98-3
Price: $30/20mg
Verbasoside

Catalog No: CFN95015
CAS No: 61548-34-3
Price: $318/5mg
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Tags: buy Abiesadine I | Abiesadine I supplier | purchase Abiesadine I | Abiesadine I cost | Abiesadine I manufacturer | order Abiesadine I | Abiesadine I distributor